Post-Graduation Program in Health Sciences - University of Southern Santa Catarina, Tubarão, SC, Brazil.
Cancer Epidemiol. 2013 Dec;37(6):788-92. doi: 10.1016/j.canep.2013.08.007. Epub 2013 Sep 10.
Despite the considerable epidemiological relevance of cancer in developing countries, there are very few studies of the burden related to cancer. The aim of this study was to present and discuss data from a burden-of-cancer study performed in a Southern Brazilian state.
An epidemiological study of ecological design was performed to calculate the disability-adjusted life year (DALY) index. The study was based on records of individuals admitted and treated for cancer in the Brazilian National Health System Hospitals, or individuals who had died of cancer while residing in the state of Santa Catarina in 2008.
A total of 73,872.9 DALYs were estimated, which generated a rate of 1220.5 DALYs/100,000 inhabitants. The highest DALYs were those for cancer of the trachea, bronchus and lung with 179.0/100,000 inhabitants, gastric cancer with 101.7/100,000 inhabitants, and breast cancer with 99.7/100,000 inhabitants. The percentage contribution of the DALY component varied according to cancer type; however, mortality was the major component in all types. The highest rates were observed in 60-69-year-olds with 6071.3/100,000 inhabitants, in 70-79-year-olds with 5095.4/100,000 inhabitants, and in 45-59-year-olds with 3189.0 DALY/100,000 inhabitants; 53.7% of DALYs occurred in males.
The greatest burden of disease due to cancer in Santa Catarina was attributed to cancer of the trachea, bronchus and lung, followed by gastric and breast cancers. The mortality component was responsible for the greatest burden.
尽管癌症在发展中国家具有相当大的流行病学意义，但对癌症相关负担的研究却很少。本研究旨在介绍和讨论在巴西南部一州进行的癌症负担研究的数据。
采用生态设计的流行病学研究来计算残疾调整生命年（DALY）指数。该研究基于 2008 年在巴西国家卫生系统医院住院和接受癌症治疗的个体，或在圣卡塔琳娜州居住期间死于癌症的个体的记录。
共估计了 73872.9 个 DALY，产生了 1220.5 DALY/100000 居民的发病率。DALY 最高的是气管、支气管和肺癌，发病率为 179.0/100000 居民，胃癌为 101.7/100000 居民，乳腺癌为 99.7/100000 居民。DALY 组成部分的百分比贡献因癌症类型而异；然而，在所有类型中，死亡率是主要组成部分。发病率最高的是 60-69 岁人群，为 6071.3/100000 居民，70-79 岁人群为 5095.4/100000 居民，45-59 岁人群为 3189.0 DALY/100000 居民；53.7%的 DALY 发生在男性。
圣卡塔琳娜州癌症的最大疾病负担归因于气管、支气管和肺癌，其次是胃癌和乳腺癌。死亡率是最大的负担。
