Fioretto José R, Carvalho Werther B
Pediatrics Department, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, São Paulo, SP, Brazil; Sociedade Paulista de Terapia Intensiva, São Paulo, SP, Brazil.
J Pediatr (Rio J). 2013 Nov-Dec;89(6):523-30. doi: 10.1016/j.jped.2013.02.023. Epub 2013 Sep 13.
to review the evolution of acute respiratory distress syndrome (ARDS) definitions and present the current definition for the syndrome.
a literature review and selection of the most relevant articles on ARDS definitions was performed using the MEDLINE®/PubMed® Resource Guide database (last ten years), in addition to including the most important articles (classic articles) that described the disease evolution.
the review included the following subjects: introduction; importance of definition; description of the first diagnostic criterion and subsequently used definitions, such as acute lung injury score; definition by the American-European Consensus Conference, and its limitations; description of the definition by Delphi, and its problems; accuracy of the aforementioned definitions; description of most recent definition (the Berlin definition), and its limitations; and practical importance of the new definition.
ARDS is a serious disease that remains an ongoing diagnostic and therapeutic challenge. The evolution of definitions used to describe the disease shows that studies are needed to validate the current definition, especially in pediatrics, where the data are very scarce.
回顾急性呼吸窘迫综合征（ARDS）定义的演变过程，并介绍该综合征的当前定义。
除纳入描述该疾病演变的最重要文章（经典文章）外，还使用MEDLINE®/PubMed®资源指南数据库（最近十年）对有关ARDS定义的文献进行了综述并挑选出最相关的文章。
综述包括以下主题：引言；定义的重要性；首个诊断标准及随后使用的定义（如急性肺损伤评分）的描述；欧美共识会议的定义及其局限性；德尔菲法定义的描述及其问题；上述定义的准确性；最新定义（柏林定义）的描述及其局限性；以及新定义的实际重要性。
ARDS是一种严重疾病，仍然是一个持续存在的诊断和治疗挑战。用于描述该疾病的定义的演变表明，需要开展研究以验证当前定义，尤其是在儿科领域，因为该领域的数据非常匮乏。
