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前瞻性研究开放腹股沟疝修补术的疼痛、生活质量和经济影响。

Prospective study of pain, quality of life and the economic impact of open inguinal hernia repair.

机构信息

Departments of Surgery, Hospital of Halland, Halmstad, Lund, Sweden.

出版信息

Br J Surg. 2013 Oct;100(11):1483-8. doi: 10.1002/bjs.9232.

Abstract

BACKGROUND

There are variations in quality of life (QoL) and reported risk of chronic pain after inguinal hernia repair. The aim of this study was to investigate the improvement in pain and QoL after open inguinal hernia repair, and the economic impact.

METHODS

Patients undergoing open mesh repair of a primary unilateral inguinal hernia were stratified depending on preoperative levels of symptoms and pain. Short Form 36 (SF-36®) and EQ-5D™ questionnaires were filled in before, and at 3 and 12 months after surgery. EQ-5D™ data, together with information on the mean value of a quality-adjusted life-year and the societal cost of hernia repair, were used to calculate the monetary value of QoL gained and the mean return on investment.

RESULTS

Of 225 patients who began the study, 184 completed follow-up at 12 months. Some 77·2 per cent reported improvement in pain and 5·4 per cent reported increased pain after surgery. Significant improvement in SF-36® scores, pain scores measured on a visual analogue scale (VAS), and symptoms were found in the majority of patients, even those with mild symptoms before surgery. For the whole group, the bodily pain score increased from 56·4 before surgery to 82·6 at 12 months after hernia repair (P < 0·050), and the VAS score decreased from a median of 4 to 0 (P < 0·050). The return on investment was positive for all groups of patients, including those with mild symptoms.

CONCLUSION

QoL improves after open inguinal hernia repair, with a good return on investment independent of symptom severity.

摘要

背景

在腹股沟疝修补术后,生活质量(QoL)和慢性疼痛风险存在差异。本研究旨在探讨开放式腹股沟疝修补术后疼痛和生活质量的改善情况,以及其经济影响。

方法

根据术前症状和疼痛程度,对接受开放式网片修补原发性单侧腹股沟疝的患者进行分层。在术前、术后 3 个月和 12 个月时填写简明 36 项健康调查量表(SF-36®)和欧洲五维健康量表(EQ-5D™)问卷。EQ-5D™数据,以及关于质量调整生命年的平均值和疝修补术社会成本的信息,用于计算生活质量改善的货币价值和平均投资回报率。

结果

在开始研究的 225 名患者中,184 名患者在 12 个月时完成了随访。77.2%的患者报告疼痛改善,5.4%的患者报告手术后疼痛增加。大多数患者,甚至是术前症状轻微的患者,在 SF-36®评分、视觉模拟量表(VAS)测量的疼痛评分和症状方面均有显著改善。对于整个组,身体疼痛评分从术前的 56.4 增加到疝修补术后 12 个月的 82.6(P<0.050),VAS 评分从中位数 4 降低到 0(P<0.050)。投资回报率对于所有患者组均为正,包括症状轻微的患者。

结论

开放式腹股沟疝修补术后生活质量改善,投资回报率良好,与症状严重程度无关。

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