a The Research Center of Psychology & Brain Science , Guangzhou University , Guangzhou , China.
J Clin Exp Neuropsychol. 2013;35(9):897-905. doi: 10.1080/13803395.2013.828022. Epub 2013 Sep 17.
There is mixed evidence concerning cognitive function and heroin dependence. In this study, abstinent heroin-dependent individuals (n = 86) and age- and sex-matched non-drug-using controls (n = 88) were compared on self-report measures of impulsivity and computerized assessments of cognitive function. Abstinent heroin-dependent individuals reported greater motor impulsivity and experience seeking and showed functional weaknesses in cognitive ability, including impulsivity and distractibility (d = 0.28 to 0.49), but not decision making or working memory. Self-reported impulsivity was uncorrelated with cognitive function. These results suggest underlying brain-related factors in heroin dependence and have implications for therapeutic intervention.
关于认知功能和海洛因依赖，目前的证据尚不一致。在这项研究中，我们对 86 名戒毒后的海洛因依赖个体和 88 名年龄和性别匹配的非吸毒对照个体进行了比较，比较的内容包括自我报告的冲动性测量和计算机认知功能评估。戒毒后的海洛因依赖个体报告了更大的运动冲动性和寻求体验，并且在认知能力方面表现出功能性弱点，包括冲动性和注意力分散（d 值为 0.28 至 0.49），但在决策或工作记忆方面没有表现出弱点。自我报告的冲动性与认知功能无关。这些结果表明海洛因依赖与大脑相关因素有关，对治疗干预具有启示意义。
