RNA polymerase II C-terminal domain: Tethering transcription to transcript and template.
作者信息
Corden Jeffry L
机构信息
Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine , 725 North Wolfe Street, Baltimore Maryland 21205, United States.
出版信息
Chem Rev. 2013 Nov 13;113(11):8423-55. doi: 10.1021/cr400158h. Epub 2013 Sep 16.
Abstract
摘要
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Phosphorylation of RNA polymerase II is independent of P-TEFb in the C. elegans germline.RNA 聚合酶 II 的磷酸化在秀丽隐杆线虫生殖系中独立于 P-TEFb。
Development. 2013 Sep;140(17):3703-13. doi: 10.1242/dev.095778. Epub 2013 Jul 31.
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Pause, play, repeat: CDKs push RNAP II's buttons.暂停、播放、重复：细胞周期蛋白依赖性激酶操控着RNA聚合酶II。
Transcription. 2013 Jul-Aug;4(4):146-52. doi: 10.4161/trns.25146. Epub 2013 Jun 11.
3
Global regulation of promoter melting in naive lymphocytes.在初始淋巴细胞中启动子融化的全球调控。
Cell. 2013 May 23;153(5):988-99. doi: 10.1016/j.cell.2013.04.033.
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A DNA damage response system associated with the phosphoCTD of elongating RNA polymerase II.一个与延伸 RNA 聚合酶 II 的磷酸化 CTD 相关的 DNA 损伤反应系统。
PLoS One. 2013 Apr 16;8(4):e60909. doi: 10.1371/journal.pone.0060909. Print 2013.
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In vivo live imaging of RNA polymerase II transcription factories in primary cells.在原代细胞中对 RNA 聚合酶 II 转录工厂进行体内实时成像。
Genes Dev. 2013 Apr 1;27(7):767-77. doi: 10.1101/gad.216200.113.
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A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.一个保守的中介物-CDK8 激酶模块关联调节中介物-RNA 聚合酶 II 相互作用。
Nat Struct Mol Biol. 2013 May;20(5):611-9. doi: 10.1038/nsmb.2549. Epub 2013 Apr 7.
7
Atomic structure and hierarchical assembly of a cross-β amyloid fibril.交叉β 淀粉样纤维的原子结构和分级组装。
Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5468-73. doi: 10.1073/pnas.1219476110. Epub 2013 Mar 19.
8
Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl-terminal domain repeat.转录延伸调控因子 TCERG1 与 RNA 聚合酶 II 的特定相互作用需要羧基末端结构域重复内丝氨酸 2、丝氨酸 5 和丝氨酸 7 的同时磷酸化。
J Biol Chem. 2013 Apr 12;288(15):10890-901. doi: 10.1074/jbc.M113.460238. Epub 2013 Feb 22.
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RNAP-II molecules participate in the anchoring of the ORC to rDNA replication origins.RNA 聚合酶 II 分子参与将 ORC 锚定到 rDNA 复制起点。
PLoS One. 2013;8(1):e53405. doi: 10.1371/journal.pone.0053405. Epub 2013 Jan 4.
10
CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo.CTD 丝氨酸-2 在体内 RNA 聚合酶 II 的剪接和终止因子募集中起着关键作用。
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