Bergman N A
Department of Anesthesiology, Oregon Health Sciences University, Portland 97201.
Anesthesiology. 1990 Jan;72(1):185-6. doi: 10.1097/00000542-199001000-00026.
Descriptions of the earliest iv injections of various substances by individuals who actually witnessed the experiments in 1656 are presented. Of particular interest is an apparently overlooked account of an experiment in which opium was administered intravenously to a dog many years before 1674 as related by the physician and anatomist Thomas Willis. He does not identify the precise date nor the experimenters. However, at the time of this event Willis would have been at Oxford. There he was a very close professional associate of Christopher Wren who originated the practice of iv injection. These eyewitness accounts are worthy of note because the articles usually cited to establish Wren as the first individual to administer a drug intravenously were not written by anyone who actually observed the experiments.
文中呈现了那些在1656年实际见证了各类物质首次静脉注射实验的人的描述。特别值得关注的是，内科医生兼解剖学家托马斯·威利斯讲述了一个显然被忽视的实验记录，即在1674年之前很多年，曾给一只狗静脉注射鸦片。他没有明确指出具体日期和实验者。然而，在这件事发生时，威利斯应该在牛津。在那里，他是静脉注射做法的开创者克里斯托弗·雷恩非常亲密的职业伙伴。这些目击者的描述值得注意，因为通常被引用来确立雷恩是第一个进行静脉药物注射的人的文章，并非由任何实际观察过这些实验的人所撰写。
