Doshi Rishi R, Lowrance Matthew D, Kim Brian T, Davis Janet L, Rosenfeld Philip J
Ophthalmic Surg Lasers Imaging Retina. 2013 Sep-Oct;44(5):508-12. doi: 10.3928/23258160-20130909-19.
High-resolution imaging with spectral-domain optical coherence tomography has identified an unusual group of epiretinal membranes (ERMs) in the presence of lamellar macular holes. These ERMs are unusually thick. The authors present the case of a patient with age-related macular degeneration who developed edema within a thickened ERM in both eyes after cataract surgery. The edema resolved with anti-vascular endothelial growth factor (VEGF) therapy. The authors propose that the VEGF-responsive fluid within these thick ERMs arose from fibrovascular tissue derived from the retina. Further studies with histopathology will be required to determine whether neovascular tissue is present in all cases of thickened ERMs with epiretinal edema.
光谱域光学相干断层扫描的高分辨率成像已在板层黄斑裂孔存在的情况下识别出一组不同寻常的视网膜前膜（ERM）。这些ERM异常增厚。作者报告了一例年龄相关性黄斑变性患者的病例，该患者在白内障手术后双眼增厚的ERM内出现水肿。水肿通过抗血管内皮生长因子（VEGF）治疗得以消退。作者提出，这些增厚的ERM内对VEGF有反应的液体源自视网膜的纤维血管组织。需要进一步进行组织病理学研究，以确定所有伴有视网膜前水肿的增厚ERM病例中是否都存在新生血管组织。
