1 Department of Neurology, Manipal Hospitals, Bangalore, Karnataka, India.
J Int Neuropsychol Soc. 2013 Nov;19(10):1109-18. doi: 10.1017/S1355617713001045. Epub 2013 Sep 18.
Prospective memory (PM) refers to the ability to remember to carry out an intended action in the future and it is pervasive in our daily living. A failure to execute an intended action (e.g., take medication) at the appropriate juncture in future (e.g., after dinner) can negatively affect our daily functioning and at times, may have devastating effects (e.g., forgetting to turn off the gas stove before leaving the house). Patients with Parkinson's disease (PD) exhibit widespread cognitive deficits including deficits in PM. The present study provides a meta-analytic review of PM in PD. Results across nine studies indicated time and event-based PM to be similarly impaired in PD, with time-based PM compromised to a slightly larger extent (Hedges' g = -0.71) as compared to event-based PM (Hedges' g = -0.55). The impairment in PM is more likely due to failure in self-initiated retrieval of intention to be executed, rather than forgetting the content of the intention itself. Furthermore, factors such as intervening task complexity and the mediating role of other executive functions have also been proposed to be responsible for impaired PM in PD.
前瞻性记忆（PM）是指在未来记住执行某项预期行动的能力，它在我们的日常生活中无处不在。未能在未来（例如，晚饭后）的适当时间执行预期的行动（例如，服药）可能会对我们的日常功能产生负面影响，有时甚至会产生灾难性的影响（例如，离开家之前忘记关闭煤气炉）。患有帕金森病（PD）的患者表现出广泛的认知缺陷，包括 PM 缺陷。本研究对 PD 中的 PM 进行了元分析综述。九项研究的结果表明，时间和基于事件的 PM 在 PD 中同样受损，基于时间的 PM 受损程度略大（Hedges'g=-0.71），而基于事件的 PM 受损程度略小（Hedges'g=-0.55）。PM 的损伤更可能是由于未能自行检索要执行的意图，而不是忘记意图本身的内容。此外，还提出了诸如干预任务复杂性和其他执行功能的中介作用等因素，这些因素也可能导致 PD 中 PM 受损。
