Lentnek A L, Giger O, O'Rourke E
Department of Medicine, Episcopal Hospital, Philadelphia, Pa.
Arch Intern Med. 1990 Jan;150(1):89-93.
Over an 18-month period, the incidence of group A beta-hemolytic streptococcal bacteremia rose from an average of 2.5 per 10,000 patient discharges to 17.9. A retrospective analysis was performed comparing patients with group A beta-hemolytic streptococcal bacteremia during this 18-month period with those who presented over the preceding 36 months. Most of the increased incidence was attributable to individuals hospitalized with a diagnosis of drug addiction who had concomitant soft-tissue infection, although the absolute number of hospitalized drug addicts did not change during this interval. No common or distinctive group A streptococcal serotypic patterns were discovered. This experience suggests that group A beta-hemolytic streptococcal bacteremia and soft-tissue infection may present in epidemic fashion among parenteral drug addicts in the absence of a common source.
在18个月的时间里，A组β溶血性链球菌菌血症的发病率从每10000例出院患者平均2.5例升至17.9例。进行了一项回顾性分析，比较了这18个月期间患有A组β溶血性链球菌菌血症的患者与前36个月就诊的患者。发病率增加的大部分原因是因药物成瘾住院且伴有软组织感染的个体，尽管在此期间住院药物成瘾者的绝对数量没有变化。未发现常见或独特的A组链球菌血清型模式。这一情况表明，在没有共同传染源的情况下，A组β溶血性链球菌菌血症和软组织感染可能在注射吸毒者中呈流行态势。
