Stene J K
Department of Anesthesia, Pennsylvania State University School of Medicine, Hershey 17033.
Crit Care Clin. 1990 Jan;6(1):111-9.
Acute renal failure is a serious complication of the resuscitation and post-traumatic critical care of the severely injured patient. Renal ischemia secondary to shock is the most common cause of post-traumatic renal failure. The unrecognized or untreated renal ischemic state can lead to nephrotoxic damage in the post-traumatic patient. Prevention of acute failure by rapid resuscitation and restoration of circulating volume to prevent ongoing renal ischemia and prerenal azotemia is imperative for reducing the incidence of post-traumatic renal failure. Once post-traumatic renal failure is established, aggressive dialysis can reduce the mortality resulting from post-traumatic renal failure.
急性肾衰竭是严重创伤患者复苏和创伤后重症监护的严重并发症。休克继发的肾缺血是创伤后肾衰竭最常见的原因。未被认识或未治疗的肾缺血状态可导致创伤后患者发生肾毒性损害。通过快速复苏和恢复循环血容量以预防持续的肾缺血和肾前性氮质血症来预防急性肾衰竭，对于降低创伤后肾衰竭的发生率至关重要。一旦创伤后肾衰竭确立，积极的透析可降低创伤后肾衰竭导致的死亡率。
