Dal T, Ciçek M, Uçmak D, Akkurt M, Tekin A, Dal M S, Tekin R, Kalkanl S T
Departments of 1Clinical Microbiology, Dicle University, Faculty of Medicine, Diyarbakır, Turkey.
Clin Ter. 2013;164(4):315-7. doi: 10.7417/CT.2013.1579.
Chronic urticaria (CU) is defined by recurrent episodes occurring at least twice a week for 6 weeks and generally characterized by the rapid appearance of wheals and/or angioedema and may be associated with parasitic infections. We aimed to investigate the seroprevalance of Toxocara canis and Fasciola species in patients with CU.
We included 55 patients (in age 16-55) with urticaria admitted in study. As a control group we recruited 30 healthy volunteers they had no history of urticaria, rhinitis, asthma, atopic eczema/dermatitis syndrome (AEDS), or other relevant diseases. IgG antibodies to Toxocara canis and Fasciola species were investigated by ELISA method.
In a total of 55 patients (mean age: 31.85 ± 8.92), 8 patients (14.5%) were positive for IgG antibodies to Toxocara canis. Among seropositive patients (mean age: 38.62 ± 12.46) 6 patients were female. No patient was positive for Fasciola by ELISA. Six of Toxocara canis seropositive cases were frequently visited or lived in rural areas and had contact with pets.
Patients with urticaria, should be tested for Toxocara canis and treated with anthelminthic drugs in endemics areas for toxocariasis.
慢性荨麻疹（CU）定义为每周至少发作两次，持续6周的复发性发作，通常表现为风团和/或血管性水肿迅速出现，可能与寄生虫感染有关。我们旨在调查慢性荨麻疹患者中犬弓首蛔虫和片形吸虫的血清流行率。
我们纳入了55名年龄在16 - 55岁之间的荨麻疹患者进行研究。作为对照组，我们招募了30名健康志愿者，他们没有荨麻疹、鼻炎、哮喘、特应性湿疹/皮炎综合征（AEDS）或其他相关疾病的病史。采用酶联免疫吸附测定（ELISA）法检测犬弓首蛔虫和片形吸虫的IgG抗体。
在总共55名患者（平均年龄：31.85±8.92岁）中，8名患者（14.5%）犬弓首蛔虫IgG抗体呈阳性。在血清阳性患者（平均年龄：38.62±12.46岁）中，6名患者为女性。ELISA法检测未发现片形吸虫阳性患者。犬弓首蛔虫血清阳性的6例患者经常前往或居住在农村地区且与宠物有接触。
荨麻疹患者在弓首蛔虫病流行地区应进行犬弓首蛔虫检测，并使用驱虫药物进行治疗。
