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Biomarkers: new biomarker for Sjögren's syndrome--time to treat patients.

作者信息

Kroese Frans G M, Bootsma Hendrika

机构信息

Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Centre Groningen, AA21, PO Box 30001, 9700 RB Groningen, Netherlands.

出版信息

Nat Rev Rheumatol. 2013 Oct;9(10):570-2. doi: 10.1038/nrrheum.2013.143. Epub 2013 Sep 17.

DOI:10.1038/nrrheum.2013.143
PMID:24045708
Abstract
摘要

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EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI) is sensitive to show efficacy of rituximab treatment in a randomised controlled trial.欧洲抗风湿病联盟干燥综合征疾病活动指数(ESSDAI)在一项随机对照试验中对显示利妥昔单抗治疗的疗效很敏感。
Ann Rheum Dis. 2014 Feb;73(2):472-4. doi: 10.1136/annrheumdis-2013-203736. Epub 2013 Aug 12.
2
Predominantly proinflammatory cytokines decrease after B cell depletion therapy in patients with primary Sjogren's syndrome.在原发性干燥综合征患者中,B细胞清除疗法后主要促炎细胞因子减少。
Ann Rheum Dis. 2013 Dec;72(12):2048-50. doi: 10.1136/annrheumdis-2013-203447. Epub 2013 Jul 17.
3
MxA as a clinically applicable biomarker for identifying systemic interferon type I in primary Sjogren's syndrome.
MxA 作为一种临床应用的生物标志物,可用于鉴定原发性干燥综合征中的系统性 I 型干扰素。
Ann Rheum Dis. 2014 Jun;73(6):1052-9. doi: 10.1136/annrheumdis-2012-202552. Epub 2013 Jul 6.
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The interferon signature in autoimmune diseases.自身免疫性疾病中的干扰素特征。
Curr Opin Rheumatol. 2013 Mar;25(2):248-53. doi: 10.1097/BOR.0b013e32835c7e32.
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Topical and systemic medications for the treatment of primary Sjögren's syndrome.原发性干燥综合征的局部和全身药物治疗。
Nat Rev Rheumatol. 2012 May 1;8(7):399-411. doi: 10.1038/nrrheum.2012.53.
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The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients.类风湿关节炎患者对利妥昔单抗无反应的干扰素 I 型特征预测。
Arthritis Res Ther. 2012 Apr 27;14(2):R95. doi: 10.1186/ar3819.
7
EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjogren's syndrome.EULAR 干燥综合征患者报告指数(ESSPRI):原发性干燥综合征共识患者指数的制定。
Ann Rheum Dis. 2011 Jun;70(6):968-72. doi: 10.1136/ard.2010.143743. Epub 2011 Feb 22.
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EULAR Sjogren's syndrome disease activity index: development of a consensus systemic disease activity index for primary Sjogren's syndrome.EULAR 干燥综合征疾病活动指数:原发性干燥综合征共识系统性疾病活动指数的制定。
Ann Rheum Dis. 2010 Jun;69(6):1103-9. doi: 10.1136/ard.2009.110619. Epub 2009 Jun 28.
9
Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome.原发性干燥综合征靶器官中干扰素通路的激活及浆细胞样树突状细胞募集
Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2770-5. doi: 10.1073/pnas.0510837103. Epub 2006 Feb 13.
10
Gene expression profiling of minor salivary glands clearly distinguishes primary Sjögren's syndrome patients from healthy control subjects.小唾液腺的基因表达谱分析能明确区分原发性干燥综合征患者与健康对照者。
Arthritis Rheum. 2005 May;52(5):1534-44. doi: 10.1002/art.21006.