Hokkaido Medical Center for Rheumatic Diseases, 1-45, 3-Chome, 1-Jo, Kotoni, Nishi-ku, Sapporo 063-0811, Japan.
Rheumatology (Oxford). 2014 Apr;53(4):586-91. doi: 10.1093/rheumatology/ket311. Epub 2013 Sep 18.
RA is a condition of multiple synovitis. Abnormal synovial vascularity (SV) is evident with the onset of joint inflammation. The idea of estimating the level of joint inflammation by sonographic SV was conceived with the advancement of US. The ideal treatment strategy, called treat to target (T2T), requires early diagnosis and assessment of RA. Detection of positive SV can be useful for proving the presence of synovitis and finally diagnosing RA. In the assessment of RA, US-based global scores aimed at assessing overall disease activity have the potential to be useful for the achievement of T2T because US can directly detect changes in synovitis. Remaining SV in local joints increases the risk of structural deterioration. RA requires both improvement of overall disease activity and the disappearance of local SV for remission. The evaluation of SV provides various information and contributes to the clinical treatment of RA.
类风湿关节炎是一种多发性滑膜炎。关节炎症发作时，滑膜血管会出现异常。随着超声技术的进步，人们开始设想通过超声评估滑膜血管来估计关节炎症的程度。理想的治疗策略称为“达标治疗”（Treat to target，T2T），这需要早期诊断和评估类风湿关节炎。检测阳性的滑膜血管血流（SV）有助于证明滑膜炎的存在，并最终诊断类风湿关节炎。在评估类风湿关节炎时，基于超声的整体评分旨在评估整体疾病活动度，这对于实现 T2T 可能是有用的，因为超声可以直接检测滑膜炎的变化。局部关节中残留的 SV 会增加结构恶化的风险。类风湿关节炎需要改善整体疾病活动度和消除局部 SV 以达到缓解。评估 SV 可提供多种信息，并有助于类风湿关节炎的临床治疗。
