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Commissioning of the discrete spot scanning proton beam delivery system at the University of Texas M.D. Anderson Cancer Center, Proton Therapy Center, Houston.在德克萨斯大学 MD 安德森癌症中心质子治疗中心，对离散点扫描质子束传输系统进行调试。
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The M. D. Anderson proton therapy system.MD安德森质子治疗系统。
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Secondary neutrons in clinical proton radiotherapy: a charged issue.临床质子放疗中的次级中子：一个充满争议的问题。
Radiother Oncol. 2008 Feb;86(2):165-70. doi: 10.1016/j.radonc.2007.12.003. Epub 2008 Jan 14.
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Comparative treatment planning on localized prostate carcinoma conformal photon- versus proton-based radiotherapy.局限性前列腺癌基于适形光子与质子放疗的比较治疗计划
Strahlenther Onkol. 2005 Jul;181(7):448-55. doi: 10.1007/s00066-005-1317-7.
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Evaluation of the gamma dose distribution comparison method.伽马剂量分布比较方法的评估
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CERR: a computational environment for radiotherapy research.CERR：一种用于放射治疗研究的计算环境。
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Dosimetry techniques for narrow proton beam radiosurgery.窄质子束放射外科的剂量测定技术。
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The precision of proton range calculations in proton radiotherapy treatment planning: experimental verification of the relation between CT-HU and proton stopping power.质子放射治疗计划中质子射程计算的精度：CT值与质子阻止本领关系的实验验证
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应用人体前列腺模型对斑点扫描束质子治疗进行质量保证评估。

Quality assurance evaluation of spot scanning beam proton therapy with an anthropomorphic prostate phantom.

机构信息

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

出版信息

Br J Radiol. 2013 Nov;86(1031):20130390. doi: 10.1259/bjr.20130390. Epub 2013 Sep 18.

DOI:10.1259/bjr.20130390
PMID:24049129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3830437/
Abstract

OBJECTIVE

The purpose of this study was to evaluate spot scanning proton therapy with an anthropomorphic prostate phantom at the Proton Therapy Center of The University of Texas MD Anderson Cancer Center at Houston, TX (PTCH).

METHODS

An anthropomorphic prostate phantom from the Radiological Physics Center (RPC), The University of Texas MD Anderson Cancer Center, Houston, TX, was used, which contained thermoluminescent dosemeters and GAFCHROMIC(®) EBT2 film (ISP Technologies, Wayne, NJ). The phantom was irradiated by the Hitachi synchrotron (Hitachi America, Ltd, Tarrytown, NY), and the results were compared between the treatment planning system (TPS) and RPC measurements.

RESULTS

RPC results show that the right/left, inferior/superior and posterior/anterior aspects of the coronal/sagittal and EBT2 film measurements were within ±7%/±4 mm of the TPS. The RPC thermoluminescent dosemeter measurements of the prostate and femoral heads were within 3% of the TPS.

CONCLUSION

The RPC prostate phantom is a useful mechanism to evaluate spot scanning beam proton therapy within certain confidence levels.

ADVANCES IN KNOWLEDGE

The RPC anthropomorphic prostate phantom could be used to establish quality assurance of spot scanning proton beam for patients with prostate cancer.

摘要

目的

本研究旨在评估位于德克萨斯州休斯顿的德克萨斯大学 MD 安德森癌症中心质子治疗中心（PTCH）的人体前列腺模型的点扫描质子治疗。

方法

使用来自德克萨斯大学 MD 安德森癌症中心放射物理中心（RPC）的人体前列腺模型，该模型包含热释光剂量计和 GAFCHROMIC® EBT2 胶片（ISP Technologies，Wayne，NJ）。该模型由日立同步加速器（日立美国公司，Tarrytown，NY）照射，将治疗计划系统（TPS）与 RPC 测量结果进行比较。

结果

RPC 结果表明，冠状面/矢状面和 EBT2 胶片测量的右侧/左侧、下侧/上侧和后侧/前侧与 TPS 的差异在±7%/±4mm 以内。RPC 热释光剂量计测量的前列腺和股骨头与 TPS 的差异在 3%以内。

结论

RPC 前列腺模型是在一定置信水平下评估点扫描质子束治疗的有用机制。

知识进展

RPC 人体前列腺模型可用于为前列腺癌患者建立点扫描质子束的质量保证。