Kourti Maria, Mantadakis Elpidoforos, Anastasiou Athanassia, Koliouskas Dimitrios
Department of Pediatric Oncology, Hippokration General Hospital, Thessaloniki, Greece.
Indian J Med Paediatr Oncol. 2013 Apr;34(2):99-100. doi: 10.4103/0971-5851.116188.
Non-Hodgkin lymphoma (NHL) accounts for 10% of pediatric malignancies and is the third most common malignancy in childhood. We report a previous healthy 3-year-old boy with stage IV Burkitt lymphoma presenting with acute visual loss. In funduscopy his pupils were fixed at 6 mm in diameter without light perception. He started therapy according to the UKCCSG 9003 protocol. The boy didn't show any visual improvement but some slight light perception despite his partial remission after CYVE II. He died of neutropenic septicemia before his scheduled radiotherapy. In conclusion, loss of vision is a rare presenting sign in NHL. Differential diagnosis is crucial as early diagnosis and effective treatment are important for survival as well as for visual restoration.
非霍奇金淋巴瘤（NHL）占儿童恶性肿瘤的10%，是儿童期第三常见的恶性肿瘤。我们报告一名既往健康的3岁男孩，患有IV期伯基特淋巴瘤，表现为急性视力丧失。眼底检查显示，他的瞳孔固定在直径6毫米，无光感。他开始按照UKCCSG 9003方案进行治疗。尽管在CYVE II治疗后部分缓解，但该男孩视力未改善，仅有轻微光感。他在预定放疗前死于中性粒细胞减少性败血症。总之，视力丧失是NHL罕见的表现症状。鉴别诊断至关重要，因为早期诊断和有效治疗对生存以及视力恢复都很重要。
