糖尿病与牙周病双向关系中的分子机制。
Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease.
作者信息
Grover Harpreet Singh, Luthra Shailly
机构信息
Department of Periodontics and Oral Implantology, SGT Dental College, Hospital and Research Institute, Gurgaon, Haryana, India.
出版信息
J Indian Soc Periodontol. 2013 May;17(3):292-301. doi: 10.4103/0972-124X.115642.
Both diabetes and periodontitis are chronic diseases. Diabetes has many adverse effects on the periodontium, and conversely periodontitis may have deleterious effects further aggravating the condition in diabetics. The potential common pathophysiologic pathways include those associated with inflammation, altered host responses, altered tissue homeostasis, and insulin resistance. This review examines the relationship that exists between periodontal diseases and diabetes mellitus with a focus on potential common pathophysiologic mechanisms.
糖尿病和牙周炎均为慢性疾病。糖尿病对牙周组织有诸多不良影响，反之，牙周炎也可能产生有害作用，进一步加重糖尿病患者的病情。潜在的共同病理生理途径包括与炎症、宿主反应改变、组织稳态改变及胰岛素抵抗相关的途径。本综述探讨牙周疾病与糖尿病之间的关系，重点关注潜在的共同病理生理机制。
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