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牙周治疗对2型糖尿病患者血糖控制改善的影响:一项随机对照临床试验。

The effect of periodontal therapy on the improvement of glycemic control in patients with type 2 diabetes mellitus: A randomized controlled clinical trial.

作者信息

Singh Sukhdeep, Kumar Veerendra, Kumar Sheela, Subbappa Anitha

机构信息

Department of Periodontics, JSS Dental College and Hospital, SS Nagar, Bannimantap, Mysore - 570 015, Karnataka, India.

出版信息

Int J Diabetes Dev Ctries. 2008 Apr;28(2):38-44. doi: 10.4103/0973-3930.43097.

Abstract

AIMS

The purpose of this study is to investigate the effect of improved periodontal health on glycemic control in type 2 diabetes mellitus (type 2 DM) patients who have generalized periodontitis.

MATERIALS AND METHODS

A total of 45 type 2 DM patients with generalized periodontitis were selected for the study. The selected patients were randomly assigned to three groups (groups A, B, and C) comprising 15 patients each: * Group A received treatment with scaling and root planing only. * Group B received treatment with scaling and root planing followed by systemic doxycycline. * Group C received no treatment (control group). The periodontal parameters recorded included plaque index, gingival index, probing pocket depth, and clinical attachment level. These parameters were recorded at baseline (day zero), at 1 month, and at the end of 3 months. The following metabolic parameters were recorded: fasting blood glucose (FBG), postprandial blood glucose (PPBG), and glycated hemoglobin. These were recorded at baseline (day zero) and at the end of 3 months.

STATISTICAL ANALYSIS

All the parameters were subjected to repeated-measures ANOVA and Scheffe's post hoc test.

RESULTS

A statistically significant effect could be demonstrated for periodontal parameters for both group A and group B (treatment groups). Glycated hemoglobin values showed statistically significant decrease in treatment groups compared to the control group, with group B showing more significant decrease than group A.

CONCLUSIONS

The results of this study showed that nonsurgical periodontal treatment is associated with improved glycemic control in type 2 DM patients.

摘要

目的

本研究旨在调查改善牙周健康对患有广泛性牙周炎的2型糖尿病(2型DM)患者血糖控制的影响。

材料与方法

共选取45例患有广泛性牙周炎的2型DM患者进行研究。所选患者被随机分为三组(A组、B组和C组),每组15例:

  • A组仅接受龈上洁治和根面平整治疗。

  • B组接受龈上洁治和根面平整治疗,随后全身应用强力霉素。

  • C组不接受治疗(对照组)。记录的牙周参数包括菌斑指数、牙龈指数、探诊深度和临床附着水平。这些参数在基线(第0天)、1个月时和3个月末记录。记录以下代谢参数:空腹血糖(FBG)、餐后血糖(PPBG)和糖化血红蛋白。这些参数在基线(第0天)和3个月末记录。

统计分析

所有参数均进行重复测量方差分析和谢费尔事后检验。

结果

A组和B组(治疗组)的牙周参数有统计学显著效果。与对照组相比,治疗组的糖化血红蛋白值有统计学显著下降,B组下降比A组更显著。

结论

本研究结果表明,非手术牙周治疗与2型DM患者血糖控制改善有关。

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