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前列腺癌的局部低剂量率近距离放射治疗。

Focal low-dose rate brachytherapy for the treatment of prostate cancer.

机构信息

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

出版信息

Cancer Manag Res. 2013 Sep 13;5:315-25. doi: 10.2147/CMAR.S33056. eCollection 2013.

DOI:10.2147/CMAR.S33056
PMID:24049459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3775638/
Abstract

Whole-gland low-dose rate (LDR) brachytherapy has been a well-established modality of treating low-risk prostate cancer. Treatment in a focal manner has the advantages of reduced toxicity to surrounding organs. Focal treatment using LDR brachytherapy has been relatively unexplored, but it may offer advantages over other modalities that have established experiences with a focal approach. This is particularly true as prostate cancer is being detected at an earlier and more localized stage with the advent of better detection methods and newer imaging modalities.

摘要

全腺体低剂量率(LDR)近距离放射治疗已成为治疗低危前列腺癌的一种成熟模式。局部治疗具有降低周围器官毒性的优势。使用 LDR 近距离放射治疗进行局部治疗相对较少被探索,但它可能比其他具有局部治疗经验的治疗方式具有优势。随着更好的检测方法和新的成像方式的出现,前列腺癌在更早和更局限的阶段被发现,这种情况尤其如此。

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本文引用的文献

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Stereotactic body radiotherapy with a focal boost to the MRI-visible tumor as monotherapy for low- and intermediate-risk prostate cancer: early results.磁共振成像可见肿瘤立体定向体部放疗局部加量作为低危和中危前列腺癌的单药治疗:初步结果。
Radiat Oncol. 2013 Apr 9;8:84. doi: 10.1186/1748-717X-8-84.
2
Evolution of the concept of focal therapy for prostate cancer.前列腺癌局部治疗概念的演变。
Oncology (Williston Park). 2013 Jan;27(1):64-8, 70; discussion 70.
3
Focal high-dose-rate brachytherapy: a dosimetric comparison of hemigland vs. conventional whole-gland treatment.
局部高剂量率近距离放射治疗:半腺体与传统全腺体治疗的剂量学比较
Brachytherapy. 2013 Sep-Oct;12(5):434-41. doi: 10.1016/j.brachy.2012.09.002. Epub 2013 Feb 11.
4
Updated results of magnetic resonance imaging guided partial prostate brachytherapy for favorable risk prostate cancer: implications for focal therapy.磁共振引导下部分前列腺近距离放射治疗低危前列腺癌的更新结果:对局限性治疗的影响。
J Urol. 2012 Oct;188(4):1151-6. doi: 10.1016/j.juro.2012.06.010. Epub 2012 Aug 15.
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Focal therapy for localised unifocal and multifocal prostate cancer: a prospective development study.局限性单灶和多灶前列腺癌的局部治疗:一项前瞻性发展研究。
Lancet Oncol. 2012 Jun;13(6):622-32. doi: 10.1016/S1470-2045(12)70121-3. Epub 2012 Apr 17.
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Focal cryotherapy for clinically unilateral, low-intermediate risk prostate cancer in 73 men with a median follow-up of 3.7 years.73 例临床单侧、中低危前列腺癌患者行局灶冷冻治疗,中位随访时间 3.7 年。
Eur Urol. 2012 Jul;62(1):55-63. doi: 10.1016/j.eururo.2012.03.006. Epub 2012 Mar 21.
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Report of a consensus meeting on focal low dose rate brachytherapy for prostate cancer.前列腺癌局部低剂量率近距离放射治疗共识会议报告。
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