Department of Traditional Chinese Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taiwan; School of Traditional Chinese Medicine, Chang Gung University, Taiwan.
Complement Ther Med. 2013 Oct;21(5):525-8. doi: 10.1016/j.ctim.2013.08.005. Epub 2013 Aug 19.
Presentation of a case illustrating the benefits of traditional Chinese herbal granules for treatment of immune thrombocytopenic purpura in children.
A 4-year-old girl presented with persistent immune thrombocytopenic purpura refractory to the first-line conventional treatment of steroids and intravenous immunoglobulin over 7 months. She was brought to the traditional Chinese medical clinic at the Chang Gung Memorial Hospital in 2011 for alternative therapy. She received a modified Chinese herbal formula, Zi-Ying-Jiang-Huo-Tang (Phellodendri Combination), for 6 months and was followed clinically by both a pediatrician and a traditional Chinese medical doctor. The patient had a dramatic improvement in platelet count and entered complete remission after treatment with the traditional Chinese medicine. There was no recurrence of disease or side effects of treatment noted during the 12-month follow-up period.
Our case report suggests that collaborative monitoring of treatments with traditional Chinese medicine may prove beneficial in the management of childhood persistent immune thrombocytopenic purpura. A larger clinical study is warranted for further evaluation of the role of Zi-Ying-Jiang-Huo-Tang in treating immune thrombocytopenic purpura.
介绍一个病例，说明中药颗粒治疗儿童免疫性血小板减少性紫癜的疗效。
一名 4 岁女孩持续患有免疫性血小板减少性紫癜，对皮质类固醇和静脉注射免疫球蛋白的一线常规治疗 7 个月以上无效。2011 年，她因其他治疗方法被带到长庚纪念医院的中医诊所。她接受了改良的中药方剂，自拟银翘藿汤（黄柏组合）治疗 6 个月，并由儿科医生和中医医生进行临床随访。患者血小板计数显著改善，经中药治疗后完全缓解。在 12 个月的随访期间，未发现疾病复发或治疗副作用。
我们的病例报告表明，与传统中药联合监测治疗可能有助于儿童持续性免疫性血小板减少性紫癜的管理。需要进行更大规模的临床研究，以进一步评估自拟银翘藿汤在治疗免疫性血小板减少性紫癜中的作用。
