The naturally occurring rhythm of blues: winter depression.

Winter depression, a form of seasonal affective disorder, is a common condition that increases in prevalence in northern areas and in regions with a high proportion of overcast fall and winter days. Parts of Ohio are high-risk areas given the high percentage of overcast days. Winter depression is marked by the onset of recurrent episodes of major depression each fall or winter which spontaneously remit in the spring. The depressive syndrome is often characterized by sadness, anxiety, decreased involvement in work and social activities, increased appetite, carbohydrate craving, weight gain, hypersomnia and psychomotor retardation. This syndrome often responds to treatment with two to six hours per day of full-spectrum bright artificial light. The efficacy of drugs in the treatment of this condition is now being studied at The Ohio State University. A monoamine oxidase inhibitor is effective.