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髂动脉闭塞性疾病的双功能超声引导经皮腔内血管成形术。

Duplex-guided percutaneous transluminal angioplasty in iliac arterial occlusive disease.

机构信息

Department of Surgery, Division of Vascular Surgery, Atrium Medical Centre, Heerlen, The Netherlands.

出版信息

Eur J Vasc Endovasc Surg. 2013 Nov;46(5):583-7. doi: 10.1016/j.ejvs.2013.08.011. Epub 2013 Sep 3.

Abstract

BACKGROUND

Chronic renal insufficiency (CRI) is a growing global problem. PTA can be performed without nephrotoxic contrast, utilizing Doppler-ultrasound (Duplex) guidance. Duplex-guided infra-inguinal interventions and access-related interventions have been reported. Duplex-guided iliac interventions have not been performed to any extent because of the anatomic location. In our study we evaluated the safety and efficacy of Duplex-guided percutaneous transluminal angioplasty (DuPTA) in iliac arteries.

METHODS

From June 2012 until February 2013, 31 patients (35 iliac lesions), underwent DuPTA. Indications ranged from Rutherford 3 to 5. Preoperative evaluation included Ankle Brachial Index (ABI), Duplex and MRA. Procedural success was defined as crossing the lesion with a guidewire and dilating or stenting the lesion. Clinical success was defined as 50% reduction in peak systolic velocity (PSV) or clinical improvement. PSV was evaluated after PTA, then at 2 weeks. Clinical results were assessed 2 weeks after the procedure.

RESULTS

Procedural success was achieved in 94% of patients (33/35), all of whom also had clinical success. Post-procedural PSV reduction showed an average improvement of 63% (431 cm/s to 153 cm/s). Mean preoperative ABI was 0.72 and improved to 0.88 postoperatively.

CONCLUSIONS

PTA using Duplex-guidance in significant iliac stenosis is a safe method with major advantages in patients at high risk for developing contrast-induced nephropathy.

摘要

背景

慢性肾功能不全(CRI)是一个日益严重的全球性问题。经皮腔内血管成形术(PTA)可以在不使用肾毒性造影剂的情况下进行,利用多普勒超声(双功)引导。已经报道了双功引导的下肢动脉腔内干预和通路相关干预。由于解剖位置的原因,双功引导的髂动脉干预尚未进行到任何程度。在我们的研究中,我们评估了双功引导经皮腔内血管成形术(DuPTA)在髂动脉中的安全性和有效性。

方法

从 2012 年 6 月至 2013 年 2 月,31 名患者(35 条髂动脉病变)接受了 DuPTA。适应证范围从 Rutherford 3 级到 5 级。术前评估包括踝肱指数(ABI)、双功超声和 MRA。手术成功定义为导丝穿过病变并扩张或支架置入病变。临床成功定义为收缩期峰值流速(PSV)降低 50%或临床改善。PTA 后评估 PSV,然后在 2 周时评估。术后 2 周评估临床结果。

结果

94%的患者(33/35)达到了手术成功,所有患者也都达到了临床成功。术后 PSV 降低显示平均改善 63%(431cm/s 至 153cm/s)。术前平均 ABI 为 0.72,术后提高至 0.88。

结论

在有发生对比剂肾病高风险的患者中,使用双功引导的 PTA 治疗髂动脉严重狭窄是一种安全的方法,具有显著优势。

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