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评估心肺功能和运动特征与睡眠阶段分类的关系。

An evaluation of cardiorespiratory and movement features with respect to sleep-stage classification.

出版信息

IEEE J Biomed Health Inform. 2014 Mar;18(2):661-9. doi: 10.1109/JBHI.2013.2276083.

Abstract

Polysomnography (PSG) is considered the gold standard to assess sleep accurately, but it can be expensive, time-consuming, and uncomfortable, specifically in long-term sleep studies. Actigraphy, on the other hand, is both cheap and userfriendly, but depending on the application lacks detail and accuracy. Our aim was to evaluate cardiorespiratory and movement signals in discriminating between wake, rapid-eye-movement (REM), light (N1N2), and deep (N3) sleep. The dataset comprised 85 nights of PSG from a healthy population. Starting from a total of 750 characteristic variables (features), problem-specific subsets of 40 features were forwardly selected using the combination of a wrapper method (Cohen's kappa statistic on radial basis function (RBF)-kernel support vector machine (SVM) classifier) and filter method (minimum redundancy maximum relevance criterion on mutual information). Final classification was performed using an RBF-kernel SVM. Non-subject-specific wake versus sleep classification resulted in a Cohen’s kappa value of 0.695, while REM versus NREM resulted in 0.558 and N3 versus N1N2 in 0.553. The broad pool of initial features gave insight in which features discriminated best between the different classes. The classification results demonstrate the possibility of making long-term sleep monitoring more widely available.

摘要

多导睡眠图(PSG)被认为是准确评估睡眠的金标准,但它既昂贵又耗时,而且不舒服,特别是在长期睡眠研究中。另一方面,运动描记术既便宜又用户友好,但根据应用的不同,它缺乏细节和准确性。我们的目的是评估心肺和运动信号在区分清醒、快速眼动(REM)、浅(N1N2)和深(N3)睡眠中的作用。该数据集由来自健康人群的 85 个 PSG 夜组成。从总共 750 个特征变量(特征)开始,使用包装器方法(Cohen's kappa 统计量的径向基函数(RBF)-核支持向量机(SVM)分类器)和过滤器方法(互信息的最小冗余最大相关性标准)向前选择 40 个特征的特定于问题的子集。最终的分类使用 RBF 核 SVM 进行。非特定于受试者的清醒与睡眠分类的 Cohen's kappa 值为 0.695,而 REM 与 NREM 的 Cohen's kappa 值为 0.558,N3 与 N1N2 的 Cohen's kappa 值为 0.553。初始特征的广泛池深入了解了哪些特征在不同类别之间具有最佳区分能力。分类结果表明,有可能使长期睡眠监测更广泛地普及。

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