Piasecka Katarzyna, Bednarski Maciej, Nawrocka Zofia, Nawrocki Jerzy, Michalewska Zofia
Oddział Okulistyczny III Szpitala Miejskiego im. dr. K. Jonschera w Łodzi.
Klin Oczna. 2013;115(2):125-9.
To compare the diagnostic ability of Heidelberg Retina Tomograph 3 and Spectral Domain Optical Coherence Tomography Copernicus in detection of optic disc changes in glaucomatous patients.
Retrospective analysis of 24 eyes of 24 subjects with primary open angle glaucoma. All individuals had complete ophthalmic examination, Heidelberg Retina Tomograph 3 and Spectral Domain Optical Coherence Tomography examinations performed. Measurements in Spectral Domain Optical Coherence Tomography were obtained both automatically (Spectral Domain Optical Coherence Tomography software) and manually. Following diameters were analyzed: disc area, cup area, cup volume, C to D ratio (C/D ratio) and circumpapillary retinal nerve fiber layer thickness.
Disc area, cup area, cup volume were classified as within normal limits more often in Spectral Domain Optical Coherence Tomography printouts than in Heidelberg Retina Tomograph (75%, 63% and 83% in SD-OCT auto, 70%, 57% and 83% in SD-OCT manu vs. 58%, 37% and 33% in Heidelberg Retina Tomograph, respectively). C/D ratio was increased in 23 eyes (96%) in Heidelberg Retina Tomograph compared to 14 eyes (58%) in SD-OCT auto and 12 eyes (52%) in SD-OCT manu. Retinal nerve fiber layer thickness was significantly lower in Spectral Domain Optical Coherence Tomography (both auto and manu 96% vs. 58% in Heidelberg Retina Tomograph). According to the Moorfields Regresion Analysis classification from Heidelberg Retina Tomograph, 21 eyes were diagnosed as glaucomatous (88%).
Although there was poor agreement in optic disc measurements between the two methods, both had high sensitivity in detection of glaucomatous optic disc changes (96% when retinal nerve fiber layer thickness measured by Spectral Domain Optical Coherence Tomography compared to 88% for Moorfield regresion analysis in Heidelberg Retina Tomograph). The sensitivity of diagnostic ability increases when both, Heidelberg Retina Tomograph and Spectral Domain Optical Coherence Tomography are performed.
比较海德堡视网膜断层扫描仪3（Heidelberg Retina Tomograph 3）和谱域光学相干断层扫描哥白尼系统（Spectral Domain Optical Coherence Tomography Copernicus）检测青光眼患者视盘变化的诊断能力。
对24例原发性开角型青光眼患者的24只眼进行回顾性分析。所有个体均接受了完整的眼科检查、海德堡视网膜断层扫描仪3检查和谱域光学相干断层扫描检查。谱域光学相干断层扫描的测量通过自动（谱域光学相干断层扫描软件）和手动方式进行。分析了以下直径：视盘面积、杯盘面积、杯盘容积、杯盘比（C/D比）和视乳头周围视网膜神经纤维层厚度。
与海德堡视网膜断层扫描仪相比，谱域光学相干断层扫描打印输出中视盘面积、杯盘面积、杯盘容积被分类为正常范围的情况更常见（谱域光学相干断层扫描自动测量分别为75%、63%和83%，谱域光学相干断层扫描手动测量分别为70%、57%和83%，而海德堡视网膜断层扫描仪分别为58%、37%和33%）。海德堡视网膜断层扫描仪中23只眼（96%）的C/D比升高，而谱域光学相干断层扫描自动测量中有14只眼（58%），谱域光学相干断层扫描手动测量中有12只眼（52%）。谱域光学相干断层扫描（自动和手动测量）中的视网膜神经纤维层厚度显著低于海德堡视网膜断层扫描仪（分别为96%和58%）。根据海德堡视网膜断层扫描仪的 Moorfields 回归分析分类，21只眼被诊断为青光眼（88%）。
尽管两种方法在视盘测量方面一致性较差，但两者在检测青光眼视盘变化方面均具有高敏感性（谱域光学相干断层扫描测量视网膜神经纤维层厚度时为96%，而海德堡视网膜断层扫描仪的 Moorfield 回归分析为88%）。同时进行海德堡视网膜断层扫描仪和谱域光学相干断层扫描时，诊断能力的敏感性会提高。
