Li Yan, Xu Jing, Zhang Wensheng
Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2013 Aug;30(4):905-8.
People pay more and more attention to the prolongation of QT interval caused by drugs because it could probably result in lethal arrhythmia. This article introduces mechanisms, risk factors and guidelines for QT interval, and also reviews drugs withdrawal from the market due to the results of prolongations of QT interval. It discusses as well the value of new drugs in the QT interval for the evaluation of safety.
人们越来越关注药物引起的QT间期延长，因为这可能会导致致命性心律失常。本文介绍了QT间期的机制、危险因素和指南，还回顾了因QT间期延长结果而退出市场的药物。它也讨论了新药在评估安全性方面QT间期的价值。
