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[小儿术后质量分析:疼痛与术后恶心呕吐]

[Pediatric postoperative quality analysis : Pain and postoperative nausea and vomiting].

作者信息

Balga I, Konrad C, Meissner W

机构信息

Klinik für Anästhesie, Intensivmedizin, Rettungsmedizin und Schmerztherapie, Luzerner Kantonsspital, Luzern, Schweiz,

出版信息

Anaesthesist. 2013 Sep;62(9):707-10, 712-9. doi: 10.1007/s00101-013-2211-9. Epub 2013 Sep 20.

DOI:10.1007/s00101-013-2211-9
PMID:24061870
Abstract

BACKGROUND

For the evaluation of postoperative pain therapy, nausea and vomiting (PONV), the Children's Hospital in Lucerne acts as a member of the postoperative quality improvement project QUIPSi for children. Initial results and the potential for evaluation of the postoperative pain therapy and PONV are presented here. The central questions are whether the postoperative therapy concept is sufficient and if QUIPSi serves as an ideal tool for postoperative quality improvement?

METHODS

Over a period of 1.5 years a total of 460 children aged between 4 to 17 years evaluated their postoperative pain, requirements for more analgesic medicine and the incidence of PONV according to a standardized questionnaire on the first postoperative day. The administration of analgesic medicine was recorded until finishing the questionnaire.

RESULTS

In this study 5 pediatric outpatient operation groups (hernia repair n = 36, bone surgery n = 23, metal removal surgery n = 31, circumcision n = 65 and soft tissue surgery n = 49) and 9 pediatric inpatient operation groups (appendectomy n = 21, bone surgery n = 78, metal removal surgery n = 24, orchidopexy n = 31, combined operation (orchidopexy + hernia repair or circumcision) n = 14, otoplasty n = 9, tonsillectomy n = 41 and pectus excavatum surgery n = 6 and soft tissue surgery n=28) could be classified. All operation groups except the inpatient and outpatient soft tissue surgery groups received regional or infiltration anesthesia. Analgesic medicine was prescribed with the maximum permitted daily dose per kg body weight (paracetamol 100 mg/kgBW, metamizole 80 mg/kgBW, diclofenac 3 mg/kgBW and ibuprofen 40 mg/kgBW; in reserve tramadol 8 mg/kgBW and nalbuphine 2.4 mg/kgBW). The following operation groups complained of persistent pain (scale according to Hicks 0-10) and/or required more pain medicine (%): pediatric outpatients circumcision 5.1/19 %, pediatric inpatients appendectomy 6.5/43 %, tonsillectomy 6.4/32 %, pectus excavatum surgery 7.7/33 %, orchidopexy 4.2/19.4 %, otoplasty 3.1/22.2 %. The reason for the elevated postoperative pain was mainly insufficient administered pain medicine despite the prescription of the maximum daily dose per kg body weight or maybe due to a late administration. Circumcision/appendectomy/tonsillectomy/pectus excavatum surgery/orchidopexy/otoplasty (% of max. daily dose): paracetamol 5/58/99/36/57/37 %, metamizole 0,4/18/8/54/4/4 %, diclofenac 44/45/3/97/51/68 % or ibuprofen 42/1/0/0/0/0 %, tramadol 0,4/0/0/0/0/0 %, nalbuphine 0,4/1/16/0/2/0 %). As the standard inhalative general anesthesia and PONV prophylaxis with tropisetron (body weight: < 20 kg 1 mg, > 20 kg: 2 mg intravenous bolus) was performed. Dexamethasone (0.15-0.5 mg/kgBW, maximum allowed dose 8 mg intravenous bolus) was administered as a back-up drug for PONV. The nausea incidence was higher in the inpatient group (14-50 %) than in the outpatient group (10-29 %). The incidence of vomiting was higher in the inpatient (0-37 %) than in the outpatient group (3-17 %).

CONCLUSIONS

The quality analysis showed that especially children with the requirement for more pain medicine and a high PONV incidence (inpatient group) need further improvement in postoperative care. Because of small numbers in some operation groups this qualitative evaluation of the postoperative pain and PONV management only gives an approximate overview. The results of QUIPSi uncovered gaps in the postoperative pain management which will help improve the quality in the postoperative setting. The QUIPSi approach should be integrated as a daily tool into all pediatric surgical departments.

摘要

背景

为评估术后疼痛治疗、恶心和呕吐(术后恶心呕吐)情况,卢塞恩儿童医院作为儿童术后质量改进项目QUIPSi的成员参与其中。本文展示了术后疼痛治疗和术后恶心呕吐的初步结果及评估潜力。核心问题在于术后治疗方案是否充分,以及QUIPSi是否是术后质量改进的理想工具?

方法

在1.5年的时间里,共有460名4至17岁的儿童在术后第一天根据标准化问卷评估了他们的术后疼痛、额外镇痛药需求以及术后恶心呕吐的发生率。镇痛药的使用情况记录至完成问卷时。

结果

本研究可分类出5个儿科门诊手术组(疝修补术n = 36、骨手术n = 23、内固定取出术n = 31、包皮环切术n = 65以及软组织手术n = 49)和9个儿科住院手术组(阑尾切除术n = 21、骨手术n = 78、内固定取出术n = 24、睾丸固定术n = 31、联合手术(睾丸固定术 + 疝修补术或包皮环切术)n = 14、耳整形术n = 9、扁桃体切除术n = 41以及漏斗胸手术n = 6和软组织手术n = 28)。除住院和门诊软组织手术组外,所有手术组均接受了区域或局部浸润麻醉。镇痛药的处方剂量为每千克体重每日最大允许剂量(对乙酰氨基酚100 mg/kg体重、安乃近80 mg/kg体重、双氯芬酸3 mg/kg体重以及布洛芬40 mg/kg体重;备用曲马多8 mg/kg体重和纳布啡2.4 mg/kg体重)。以下手术组存在持续性疼痛(根据希克斯量表0 - 10)和/或需要更多镇痛药(%):儿科门诊包皮环切术5.1/19%、儿科住院阑尾切除术6.5/43%、扁桃体切除术6.4/32%、漏斗胸手术7.7/33%、睾丸固定术4.2/19.4%、耳整形术3.1/22.2%。术后疼痛加剧的原因主要是尽管按每千克体重每日最大剂量处方,但镇痛药给药不足,或者可能是给药延迟。包皮环切术/阑尾切除术/扁桃体切除术/漏斗胸手术/睾丸固定术/耳整形术(最大日剂量的%):对乙酰氨基酚5/58/99/36/57/37%、安乃近0.4/18/8/54/4/4%、双氯芬酸44/45/3/97/51/68%或布洛芬42/1/0/0/0/0%、曲马多0.4/0/0/0/0/0%、纳布啡0.4/1/16/0/2/0%。采用标准吸入全身麻醉,并预防性使用托烷司琼预防术后恶心呕吐(体重:< 20 kg 1 mg,> 20 kg:2 mg静脉推注)。地塞米松(0.15 - 0.5 mg/kg体重,最大允许剂量8 mg静脉推注)作为术后恶心呕吐的备用药物。住院组的恶心发生率(14 - 50%)高于门诊组(10 - 29%)。住院组的呕吐发生率(0 - 37%)高于门诊组(3 - 17%)。

结论

质量分析表明,尤其是那些需要更多镇痛药且术后恶心呕吐发生率高的儿童(住院组),术后护理需要进一步改进。由于部分手术组样本量较小,对术后疼痛和术后恶心呕吐管理的这种定性评估仅给出了大致概述。QUIPSi的结果揭示了术后疼痛管理中的差距,这将有助于改善术后护理质量。应将QUIPSi方法作为日常工具纳入所有儿科外科科室。

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Minerva Anestesiol. 2013 Sep;79(9):1077-87. Epub 2013 Mar 19.
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A 2013 updated systematic review & meta-analysis of 36 randomized controlled trials; no apparent effects of non steroidal anti-inflammatory agents on the risk of bleeding after tonsillectomy.2013 年更新的系统评价和荟萃分析了 36 项随机对照试验;非甾体抗炎药似乎不会增加扁桃体切除术后出血的风险。
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左布比卡因用于包皮环切术后疼痛管理:骶管阻滞或阴茎背神经阻滞。
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Does take-home analgesia improve postoperative pain after elective day case surgery? A comparison of hospital vs parent-supplied analgesia.带回家使用的镇痛措施能否改善择期日间手术术后的疼痛情况?医院提供的镇痛与家长提供的镇痛之比较。
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