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泰国东北部疑似肺结核和痰抗酸杆菌涂片阴性患者中类鼻疽病的流行情况。

Prevalence of melioidosis in patients with suspected pulmonary tuberculosis and sputum smear negative for acid-fast bacilli in northeast Thailand.

出版信息

Am J Trop Med Hyg. 2013 Nov;89(5):983-985. doi: 10.4269/ajtmh.13-0286. Epub 2013 Sep 23.

Abstract

The clinical and radiological features of pulmonary melioidosis can mimic tuberculosis. We prospectively evaluated 118 patients with suspected pulmonary tuberculosis who were acid-fast bacilli (AFB) smear negative at Udon Thani Hospital, northeast Thailand. Culture of residual sputum from AFB testing was positive for Burkholderia pseudomallei in three patients (2.5%; 95% confidence interval [CI] 0.5-7.3%). We propose that in melioidosis-endemic areas, residual sputum from AFB testing should be routinely cultured for B. pseudomallei.

摘要

肺类鼻疽的临床和影像学特征可与肺结核类似。我们前瞻性评估了 118 例在泰国东北部乌隆他尼医院经抗酸杆菌(AFB)涂片检查为阴性、疑似肺结核的患者。3 例患者(2.5%;95%置信区间 [CI] 0.5-7.3%)的 AFB 检测剩余痰培养结果为伯克霍尔德菌假单胞菌阳性。我们建议在类鼻疽流行地区,应常规对 AFB 检测的剩余痰进行伯克霍尔德菌假单胞菌培养。

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