Stoohs R, Guilleminault C
Stanford University School of Medicine, Palo Alto, California.
J Clin Neurophysiol. 1990 Jan;7(1):83-92. doi: 10.1097/00004691-199001000-00007.
Obstructive sleep apnea syndrome is well known by now, but, at both extremes of age, increased upper airway resistance may lead to clinical symptoms without complete apnea. Abnormal craniofacial features appear to be responsible for the very early appearance during childhood of increased upper airway resistance. In adults, snoring, often related to partial upper airway obstruction located in the pharynx, may be associated with changes in respiratory timing and intermittent arousal. Many treatments are currently available to deal with obstructive sleep apnea syndrome. It is important to recognize the location(s) of the upper airway obstruction before considering treatment and to evaluate the associated risk factors. Early recognition of factors involved in increased upper airway resistance may allow prevention, a more efficacious approach than treatment of an already developed syndrome.
阻塞性睡眠呼吸暂停综合征如今已广为人知,但在两个年龄极端情况下,上气道阻力增加可能导致无完全呼吸暂停的临床症状。异常的颅面特征似乎是儿童期上气道阻力增加早期出现的原因。在成年人中,打鼾通常与位于咽部的部分上气道阻塞有关,可能与呼吸节律变化和间歇性觉醒有关。目前有许多治疗方法可用于处理阻塞性睡眠呼吸暂停综合征。在考虑治疗之前识别上气道阻塞的位置并评估相关危险因素很重要。早期识别涉及上气道阻力增加的因素可能有助于预防,这是一种比治疗已发展的综合征更有效的方法。