The TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, MA, USA.
Eur Heart J Acute Cardiovasc Care. 2012 Apr;1(1):9-12. doi: 10.1177/2048872612438026.
Since Herrick's description of the clinical picture of acute myocardial infarction exactly one century ago (1912), there have been three phases of therapy: Phase 1 (1912-1961, bed rest and 'expectant' treatment); Phase 2 (1961-1974, the coronary care unit); and Phase 3 (1975-present, myocardial reperfusion). We are now on the cusp of Phase 4, which comprises efforts to reduce myocardial perfusion injury as well as regenerative medicine.
自 100 年前(1912 年) Herrick 描述急性心肌梗死的临床特征以来,治疗经历了三个阶段:第一阶段(1912-1961,卧床休息和“期待”治疗);第二阶段(1961-1974,冠心病监护病房);以及第三阶段(1975 年至今,心肌再灌注)。我们现在正处于第四阶段的边缘,这一阶段包括努力减少心肌灌注损伤和再生医学。