Paraguassu Gardenia Matos, Queiroz Isaac Vieira, do Amaral Marcelo Fernando, Melo Auremir Rocha, do Lago Carlos Augusto Pereira, Crusoe-Rebello Ieda
Gen Dent. 2013 Sep-Oct;61(6):69-72.
Multiple myeloma (MM), solitary bone plasmacytoma, and extramedullary plasmacytoma are different types of plasma cell neoplasia, which is a lymphoid neoplastic proliferation of ß-cells. While MM is most frequently seen in the vertebrae and long bones, 30% of MM cases are found in the jaws. This case report presents a 58-year-old man with mandibular swelling; his medical history indicated he had a fracture of the humerus 1 month earlier. Panoramic radiography revealed a radiolucent lesion in the mandibular posterior region. Biopsy was performed and the histopathological examination indicated plasmocytoma. However, given the patient's dental and medical history, and the presence of multiple osteolytic lesions, the final diagnosis was MM. The patient underwent chemotherapy for the MM. To treat the pathological fracture of the jaw, a hemimandibulectomy was followed by the installation of a reconstructive plate.
多发性骨髓瘤（MM）、孤立性骨浆细胞瘤和髓外浆细胞瘤是浆细胞肿瘤的不同类型，浆细胞肿瘤是β细胞的一种淋巴样肿瘤性增殖。虽然MM最常见于椎骨和长骨，但30%的MM病例发生在颌骨。本病例报告介绍了一名58岁下颌肿胀男性；其病史显示1个月前肱骨骨折。全景X线片显示下颌后部区域有一透射性病变。进行了活检，组织病理学检查显示为浆细胞瘤。然而，鉴于患者的牙科和病史以及存在多个溶骨性病变，最终诊断为MM。该患者接受了MM化疗。为治疗颌骨病理性骨折，先行半侧下颌骨切除术，随后安装重建钢板。
