Kernstock C, Friebe K, Tonagel F
Augenheilkunde, Universitätskliniken Tübingen.
Klin Monbl Augenheilkd. 2013 Nov;230(11):1097-105. doi: 10.1055/s-0033-1350786. Epub 2013 Sep 24.
Optical coherence tomography (OCT) has revolutionised ophthalmology. Due to modern instruments with extremely high resolution there are more and more applications also in neuro-ophthalmological disorders. This review gives an overview on typical changes in OCT for the following diseases: autosomal dominant optic atrophy, Leber hereditary optic neuropathy, toxic, traumatic and compressive optic neuropathy, optic nerve drusen, anterior ischaemic optic neuropathy, optic disc pit, papilledema, optic neuritis (isolated or associated with multiple sclerosis or neuromyelitis optica), neurodegenerative diseases and hereditary retinal diseases. A diagnosis exclusively based on an OCT examination is not always possible, but in several diseases there are pathognomonic changes that directly lead to the correct diagnosis. Particularly with the often complex settings in neuro-ophtalmology the OCT should be seen as a supplementary modality and not as a replacement for other techniques.
光学相干断层扫描(OCT)彻底改变了眼科领域。由于现代仪器具有极高的分辨率,其在神经眼科疾病中的应用也越来越多。本综述概述了OCT在以下疾病中的典型变化:常染色体显性遗传性视神经萎缩、Leber遗传性视神经病变、中毒性、外伤性和压迫性视神经病变、视神经乳头小体、前部缺血性视神经病变、视盘凹陷、视乳头水肿、视神经炎(孤立性或与多发性硬化症或视神经脊髓炎相关)、神经退行性疾病和遗传性视网膜疾病。仅基于OCT检查进行诊断并非总是可行的,但在几种疾病中存在可直接导致正确诊断的特征性变化。特别是在神经眼科中常常复杂的情况下,OCT应被视为一种辅助手段,而不是替代其他技术。