血小板平均体积在低高密度脂蛋白胆固醇患者中升高。
Mean platelet volume is elevated in patients with low high-density lipoprotein cholesterol.
机构信息
Department of Cardiology, Suleyman Demirel University, Isparta, Turkey
Department of Cardiology, Suleyman Demirel University, Isparta, Turkey.
出版信息
Angiology. 2014 Sep;65(8):733-6. doi: 10.1177/0003319713504024. Epub 2013 Sep 23.
A low high-density lipoprotein cholesterol (HDL-C) level is a predictor of increased cardiovascular risk. We assessed the mean platelet volume (MPV) in patients with low HDL-C. We studied 59 patients with low HDL-C (HDL-C ≤35 mg/dL) and 56 control participants (HDL-C levels >35 mg/dL) with similar cardiovascular risk factors. As expected, HDL-C was significantly lower among the patients with low HDL-C than that of the control group (32 ± 3 vs 51 ± 5 mg/dL, respectively; P < .001). Platelet count was significantly lower among the patients with low HDL-C than that of the control group (213 ± 60 vs 285 ± 75 × 10(9)/L, respectively; P < .001). The MPV was significantly higher among the patients with low HDL-C than that of the control group (8.7 ± 0.6 vs 7.1 ± 0.5 fL, respectively; P < .001). We have shown that MPV was significantly elevated in patients with low HDL-C compared with control participants.
低密度脂蛋白胆固醇（HDL-C）水平低是心血管风险增加的预测因子。我们评估了低 HDL-C 患者的平均血小板体积（MPV）。我们研究了 59 名低 HDL-C（HDL-C ≤35mg/dL）患者和 56 名具有相似心血管危险因素的对照组参与者（HDL-C 水平>35mg/dL）。正如预期的那样，低 HDL-C 患者的 HDL-C 水平明显低于对照组（分别为 32±3mg/dL 和 51±5mg/dL；P<0.001）。低 HDL-C 患者的血小板计数明显低于对照组（分别为 213±60×109/L 和 285±75×109/L；P<0.001）。低 HDL-C 患者的 MPV 明显高于对照组（分别为 8.7±0.6fL 和 7.1±0.5fL；P<0.001）。我们已经表明，与对照组相比，低 HDL-C 患者的 MPV 明显升高。
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