铑(III)催化的酰胺导向的分子间 N-螯合的芳基 C-H 酰胺化反应。
Rhodium(III)-catalyzed intermolecular N-chelator-directed aromatic C-H amidation with amides.
机构信息
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences , Fuzhou, Fujian 350002, China.
出版信息
Org Lett. 2013 Oct 4;15(19):5106-9. doi: 10.1021/ol4024776. Epub 2013 Sep 25.
PMID:24066852
Abstract
Rh(III)-catalyzed intermolecular direct aromatic C-H bond amidation with amides has been accomplished under mild reaction conditions. This protocol is applicable to a broad range of N-chelator-containing arenes amidated with aromatic and aliphatic sulfonamides. A possible mechanism is proposed according to the experimental results.
摘要
铑（III）催化的酰胺与芳基分子间直接 C-H 键酰胺化反应在温和的反应条件下得以实现。该方案适用于各种含 N-螯合剂的芳基与芳基和脂肪族磺酰胺的酰胺化。根据实验结果提出了一种可能的反应机理。
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