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造血干细胞移植后儿童因双侧颈内动脉闭塞致鼻-眶-脑毛霉菌病致死

Fatal outcome of rhino-orbital-cerebral mucormycosis due to bilateral internal carotid occlusion in a child after hematopoietic stem cell transplantation.

机构信息

From the Departments of *Neurology, †Diagnostic Imaging and ‡Immunology, University Children's Hospital of Zurich, Zurich, Switzerland.

出版信息

Pediatr Infect Dis J. 2013 Oct;32(10):1149-50. doi: 10.1097/INF.0b013e31829e69e7.

DOI:10.1097/INF.0b013e31829e69e7
PMID:24067555
Abstract

Rhino-orbito-cerebral mucormycosis is a rare fulminant opportunistic fungal infection that particularly occurs in immunocompromised patients. We present a case of fatal invasive rhino-orbito-cerebral mucormycosis complicated by bilateral thrombotic occlusion of the internal carotid artery with consequent cerebral infarction in a 5-year-old boy after hematopoietic stem cell transplantation for acute pre-B-cell lymphoblastic leukemia.

摘要

鼻-眶-脑毛霉病是一种罕见的暴发性机会性真菌感染,尤其发生于免疫功能低下的患者。我们报告了一例 5 岁男孩,在因急性前 B 细胞淋巴细胞白血病行造血干细胞移植后发生致命性侵袭性鼻-眶-脑毛霉病,并伴有双侧颈内动脉血栓性闭塞,继而导致脑梗死。

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Fatal outcome of rhino-orbital-cerebral mucormycosis due to bilateral internal carotid occlusion in a child after hematopoietic stem cell transplantation.造血干细胞移植后儿童因双侧颈内动脉闭塞致鼻-眶-脑毛霉菌病致死
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