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[空气污染与呼吸道及心血管疾病:巴西圣保罗州库巴唐的一项时间序列研究]

[Air pollution and respiratory and cardiovascular diseases: a time series study in Cubatão, São Paulo State, Brazil].

作者信息

Nardocci Adelaide Cassia, Freitas Clarice Umbelino de, Ponce de Leon Antonio Carlos Monteiro, Junger Washington Leite, Gouveia Nelson da Cruz

机构信息

Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brasil.

出版信息

Cad Saude Publica. 2013 Sep;29(9):1867-76. doi: 10.1590/0102-311x00150012.

Abstract

This study evaluated the association between air pollution and hospital admissions due to respiratory and cardiovascular diseases in Cubatão, São Paulo State, Brazil. Generalized additive Poisson regression models were used to model daily concentrations of particulate matter (PM10), sulfur dioxide (SO2), and ozone (O3) and daily hospital admissions counts. Explanatory variables were temperature, relative humidity, day of the week, and holidays. For each increment of 10µg/m³ in PM10, we found an excess of 4.25 % (95%CI: 2.82; 71), 5.74% (95%CI: 3.80; 7.71), and 2.29% (95%CI: 0.86; 3.73) in admissions due to respiratory diseases for all ages, respiratory diseases in children under 5 years old, and cardiovascular diseases in adults over 39 years of age, respectively. For SO2, the increase was 3.51% (IC95%: 1.24; 5.83) for cardiovascular diseases in adults more than 39 years. For O3, the increase was 2.85% (IC95%: 0.77; 4.98) for cardiovascular diseases in adults more than 39 years of age and 3.91% (IC95%: 1.37; 6.51) for respiratory diseases in children under 5 years old. Air pollution has serious impacts on health in Cubatão, thus emphasizing the need for air quality control policies.

摘要

本研究评估了巴西圣保罗州库巴唐市空气污染与因呼吸道和心血管疾病导致的住院之间的关联。采用广义相加泊松回归模型对颗粒物(PM10)、二氧化硫(SO2)和臭氧(O3)的日浓度以及每日住院人数进行建模。解释变量包括温度、相对湿度、星期几和节假日。对于PM10每增加10µg/m³,我们发现所有年龄段因呼吸道疾病导致的住院人数分别增加4.25%(95%置信区间:2.82;7.1)、5岁以下儿童因呼吸道疾病导致的住院人数增加5.74%(95%置信区间:3.80;7.71)以及39岁以上成年人因心血管疾病导致的住院人数增加2.29%(95%置信区间:0.86;3.73)。对于SO2,39岁以上成年人因心血管疾病导致的住院人数增加3.51%(95%置信区间:1.24;5.83)。对于O3,39岁以上成年人因心血管疾病导致的住院人数增加2.85%(95%置信区间:0.77;4.98),5岁以下儿童因呼吸道疾病导致的住院人数增加3.91%(95%置信区间:1.37;6.51)。空气污染对库巴唐市的健康有严重影响,因此强调了空气质量控制政策的必要性。

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