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转移性支气管类癌的治疗性肺动脉支架置入术

Therapeutic pulmonary artery stenting for metastatic bronchial carcinoid.

作者信息

Vawdrey Daniel B F, Fitzsimmons Samantha, Veldtman Gruschen R, Carpenter John-Paul

机构信息

Wessex Cardiothoracic Centre, Southampton, UK.

出版信息

BMJ Case Rep. 2013 Sep 24;2013:bcr2013201123. doi: 10.1136/bcr-2013-201123.

DOI:10.1136/bcr-2013-201123
PMID:24068381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3794312/
Abstract

We present a case of a middle-aged man with a 3-month history of progressive shortness of breath and peripheral oedema. Ten years prior to this, he had undergone a left pneumonectomy for metastatic bronchial carcinoid. Clinical examination revealed significant right heart failure, supported by transthoracic echocardiography. CT pulmonary angiogram revealed the cause to be marked progression of the bronchial carcinoid causing severe external compression of right pulmonary artery (RPA). In view of the distressing symptoms, a palliative endovascular intervention to the RPA was attempted to relieve obstruction, improve blood flow through the right lung and offload the right ventricle. This was performed under general anaesthesia involving interventional cardiology and radiology specialists together with a specialist anaesthetic team with extensive experience of managing carcinoid patients. The result was a marked improvement in symptoms and right heart function and the patient was discharged 2 days later.

摘要

我们报告一例中年男性病例,该患者有3个月进行性气短和外周水肿病史。在此之前十年,他因转移性支气管类癌接受了左肺切除术。临床检查发现明显的右心衰竭,经胸超声心动图检查予以证实。CT肺动脉造影显示病因是支气管类癌显著进展,导致右肺动脉(RPA)严重外部受压。鉴于患者症状令人痛苦,尝试对RPA进行姑息性血管内介入治疗,以缓解梗阻,改善右肺血流并减轻右心室负荷。该治疗在全身麻醉下进行,介入心脏病学和放射学专家以及一个在管理类癌患者方面有丰富经验的专业麻醉团队共同参与。结果患者症状和右心功能显著改善,2天后出院。

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本文引用的文献

1
Metastatic carcinoid tumour mimicking cholecystitis, and a rare case of intussusception.转移性类癌肿瘤酷似胆囊炎,及一例罕见的肠套叠病例。
BMJ Case Rep. 2011 Mar 8;2011:bcr1120103530. doi: 10.1136/bcr.11.2010.3530.
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Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs).胃肠胰神经内分泌(包括类癌)肿瘤(NETs)管理指南。
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Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors: a report from the PROMID Study Group.奥曲肽长效注射剂(LAR)对转移性中肠神经内分泌肿瘤患者肿瘤生长控制效果的安慰剂对照、双盲、前瞻性、随机研究:PROMID研究组报告
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Bronchopulmonary neuroendocrine tumors.支气管肺神经内分泌肿瘤
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Carcinoid syndrome.类癌综合征
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Epidemiology and survival in patients with carcinoid disease in The Netherlands. An epidemiological study with 2391 patients.荷兰类癌病患者的流行病学与生存率。一项针对2391名患者的流行病学研究。
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