Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China ; Center for Integrative Medicine, University of Maryland, School of Medicine, 520 West Lombard Street, East Hall, Baltimore, MD 21201, USA.
Evid Based Complement Alternat Med. 2013;2013:870305. doi: 10.1155/2013/870305. Epub 2013 Aug 28.
Knee osteoarthritis (OA) manifests with pain, joint stiffness, and limited function. In traditional Chinese medicine, knee OA is differentiated into three patterns: yang deficiency and cold coagulation, kidney deficiency, and blood stasis. The objective of this study was to determine whether yang deficiency cold coagulation patients respond better to thermal laser acupuncture treatment than do non-yang deficient patients. Fifty-two patients with OA were allocated to group A (yang deficient, n = 26) or B (non-yang deficient, n = 26). All patients received a 20-min thermal laser acupuncture treatment at acupoint Dubi (ST 35) three times a week for two weeks and twice a week for another four weeks. Outcome assessments were performed immediately after the first treatment, and at weeks 2, 6, and 10. Group A function scores were significantly better than those of Group B at weeks 2 (P = 0.049), 6 (P = 0.046), and 10 (P = 0.042), but no significant differences were found between the two groups in pain and stiffness scores at any time point. No significant adverse effect was observed. The combined 10.6 μ m-650 nm laser treatment might be most beneficial to yang deficiency cold coagulation knee OA patients, particularly in improving function.
膝骨关节炎（OA）表现为疼痛、关节僵硬和功能受限。在中医中，膝骨关节炎分为三种证型：阳虚寒凝、肾虚和血瘀。本研究旨在确定阳虚寒凝型患者对热激光针灸治疗的反应是否优于非阳虚患者。52 例 OA 患者被分为 A 组（阳虚，n=26）或 B 组（非阳虚，n=26）。所有患者均接受了 20 分钟的热激光针灸治疗，每周三次，共两周，然后每周两次，共四周，在杜比穴（ST35）进行治疗。在第一次治疗后立即进行疗效评估，并在第 2、6 和 10 周进行评估。第 2、6 和 10 周时，A 组的功能评分明显优于 B 组（P=0.049、P=0.046 和 P=0.042），但两组在疼痛和僵硬评分方面在任何时间点均无显著差异。未观察到明显的不良反应。10.6μm-650nm 激光联合治疗可能对阳虚寒凝型膝骨关节炎患者最有益，特别是在改善功能方面。
