Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2013 Sep;6(3):161-5. doi: 10.3342/ceo.2013.6.3.161. Epub 2013 Sep 4.
The aims of this study were 1) to evaluate the effect of isolated uvulopalatopharyngoplasty (UPPP) on subjective obstructive sleep apnea (OSA) symptoms in adult patients regardless of the response to surgery, and ultimately 2) to investigate the differences in changes in subjective OSA symptoms between successful and unsuccessful surgery groups.
Twenty consecutive adult patients who underwent isolated UPPP were enrolled. Pre- and postoperative subjective OSA symptoms (snoring, witnessed apnea, daytime sleepiness, morning headache, daytime fatigue, restless sleep, difficulty with morning arousal) and polysomnographic data were evaluated in all subjects. Changes in subjective OSA symptoms before and after surgery were investigated in the successful (n=11) and unsuccessful (n=9) groups. Surgical success was defined as a reduction of at least 50% in the preoperative apnea-hypopnea index (AHI) and a postoperative AHI less than 20 per hour.
After isolated UPPP, all subjective OSA symptoms changed significantly in the patients, especially in the successful group. In the unsuccessful group, snoring, witnessed apnea and daytime fatigue changed significantly, while other symptoms did not change significantly after surgery.
Isolated UPPP may improve subjective OSA symptoms in adult patients whom surgery was successful or unsuccessful. However, after isolated UPPP, the improvements in subjective OSA symptoms in the unsuccessful group may be different from those in the successful group.
本研究的目的是 1)评估孤立悬雍垂腭咽成形术(UPPP)对成年患者主观阻塞性睡眠呼吸暂停(OSA)症状的影响,无论手术反应如何,最终 2)研究手术成功和不成功组之间主观 OSA 症状变化的差异。
连续纳入 20 例接受孤立 UPPP 的成年患者。所有患者均评估术前和术后主观 OSA 症状(打鼾、目击呼吸暂停、白天嗜睡、晨起头痛、白天疲劳、不安睡眠、晨起困难)和多导睡眠图数据。在手术成功组(n=11)和不成功组(n=9)中研究了手术前后主观 OSA 症状的变化。手术成功定义为术前呼吸暂停低通气指数(AHI)降低至少 50%,术后 AHI 每小时小于 20。
孤立 UPPP 后,所有患者的主观 OSA 症状均显著改善,尤其是手术成功组。在不成功组中,打鼾、目击呼吸暂停和白天疲劳显著改善,而其他症状术后无显著变化。
孤立 UPPP 可改善手术成功或不成功的成年患者的主观 OSA 症状。然而,孤立 UPPP 后,不成功组主观 OSA 症状的改善可能与成功组不同。