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当代手术治疗阻塞性睡眠呼吸暂停综合征。

Contemporary surgery for obstructive sleep apnea syndrome.

机构信息

Adjunct Clinical Professor, Department of Otolaryngology Head and Neck Surgery, Department of Psychiatry and Behavioral Science, Stanford University Sleep and Research Center, Stanford University School of Medicine, Palo Alto, USA.

出版信息

Clin Exp Otorhinolaryngol. 2009 Sep;2(3):107-14. doi: 10.3342/ceo.2009.2.3.107. Epub 2009 Sep 23.

Abstract

Surgical treatment of obstructive sleep apnea syndrome (OSAS) has been available in some form for greater than three decades. Early management for airway obstruction during sleep relied on tracheotomy which although life saving was not well accepted by patients. In the early eighties two new forms of treatment for OSAS were developed. Surgically a technique described as a uvulopalatopharyngoplasty (UPPP) was used to treat the retropalatal region for snoring and sleep apnea. Concurrently sleep medicine developed a nasal continuous positive airway pressure (CPAP) device to manage nocturnal airway obstruction. Both of these measures were used to expand and stabilize the pharyngeal airway space during sleep. The goal for each technique was to limit or alleviate OSAS. Almost 30 yr later these two treatment modalities continue to be the mainstay of contemporary treatment. As expected, CPAP device technology improved over time along with durable goods. Surgery followed suit and additional techniques were developed to treat soft and bony structures of the entire upper airway (nose, palate and tongue base). This review will only focus on the contemporary surgical methods that have demonstrated relatively consistent positive clinical outcomes. Not all surgical and medical treatment modalities are successful or even partially successful for every patient. Advances in the treatment of OSAS are hindered by the fact that the primary etiology is still unknown. However, both medicine and surgery continue to improve diagnostic and treatment methods. Methods of diagnosis as well as treatment regimens should always include both medical and surgical collaborations so the health and quality of life of our patients can best be served.

摘要

手术治疗阻塞性睡眠呼吸暂停综合征(OSAS)已经有三十多年的历史了。早期治疗睡眠期间气道阻塞的方法依赖于气管切开术,虽然这种方法可以救命,但患者并不接受。八十年代早期,有两种新的 OSAS 治疗方法被开发出来。在手术方面,一种被称为悬雍垂腭咽成形术(UPPP)的技术被用于治疗打鼾和睡眠呼吸暂停的后咽。同时,睡眠医学开发了一种鼻腔持续气道正压通气(CPAP)装置来治疗夜间气道阻塞。这两种措施都被用来扩大和稳定睡眠期间的咽气道空间。每种技术的目标都是限制或缓解 OSAS。近 30 年后,这两种治疗方法仍然是当代治疗的主要方法。正如预期的那样,随着时间的推移,CPAP 设备技术得到了改进,耐用消费品也得到了改进。手术也随之跟进,开发了额外的技术来治疗整个上气道的软组织和骨结构(鼻子、 palate 和舌基)。本综述仅关注当代手术方法,这些方法已经证明了相对一致的积极临床效果。并非所有的手术和医疗治疗方法对每个患者都是成功的,甚至有些方法对部分患者是无效的。OSAS 的治疗进展受到其主要病因仍不清楚的限制。然而,医学和外科都在不断改进诊断和治疗方法。诊断方法以及治疗方案都应该始终包括医学和外科的合作,以便为我们的患者提供最佳的健康和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65f9/2751873/4161d73b1b44/ceo-2-107-g001.jpg

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