Park Hyoung Keun, Paick Sung Hyun, Kim Hyeong Gon, Park Doo-Heum, Cho Jae Hoon, Hong Seok-Chan, Choi Woo Suk
Department of Urology, Konkuk University School of Medicine, Seoul, Korea.
Department of Neuropsychiatry, Konkuk University School of Medicine, Seoul, Korea.
Int Neurourol J. 2016 Dec;20(4):329-334. doi: 10.5213/inj.1632624.312. Epub 2016 Dec 26.
To evaluate changes in nocturia after surgical correction of obstructive sleep apnea (OSA).
A total of 66 patients were included in the present study. All had been diagnosed with OSA syndrome by polysomnography and underwent uvulopalatopharyngoplasty (UPPP). Preoperative and postoperative lower urinary tract symptoms (LUTS), quality of life (QoL), and nocturia episodes were evaluated using the International Prostate Symptom Score (IPSS) and overactive bladder symptom score (OABSS) questionnaires. Three months postoperatively, telephone interviews were performed to determine the success of surgery, current LUTS, and nocturia episodes. Patients were divided into surgical success and failure groups. Surgical success was defined as snoring decrease more than 50% based on the patient's subjective judgment.
The response rate was 56% and success rate was 73%. In all patients, nocturia episodes significantly decreased from 1.7±1.1 to 0.8±1.2 (P=0.002). Mean IPSS score, OABSS score, and QoL scores were also significantly improved. The success group showed a significant decrease in nocturia episodes, and total IPSS, OABSS, and QoL scores. However, the failure group did not show significant changes in all parameters.
OSA correction improved nocturia as well as other LUTS. These improvements were not observed in the failure group. This study shows that OSA is a cause of nocturia and that other LUTS and nocturia can be improved by surgical correction of OSA.
评估阻塞性睡眠呼吸暂停(OSA)手术矫正后夜尿症的变化。
本研究共纳入66例患者。所有患者均通过多导睡眠图诊断为OSA综合征,并接受了悬雍垂腭咽成形术(UPPP)。使用国际前列腺症状评分(IPSS)和膀胱过度活动症症状评分(OABSS)问卷评估术前和术后的下尿路症状(LUTS)、生活质量(QoL)和夜尿发作次数。术后三个月,进行电话访谈以确定手术的成功率、当前的LUTS和夜尿发作次数。患者被分为手术成功组和失败组。手术成功定义为根据患者的主观判断打鼾减少超过50%。
应答率为56%,成功率为73%。所有患者的夜尿发作次数从1.7±1.1显著减少至0.8±1.2(P = 0.002)。平均IPSS评分、OABSS评分和QoL评分也显著改善。成功组的夜尿发作次数以及总IPSS、OABSS和QoL评分显著降低。然而,失败组的所有参数均未显示出显著变化。
OSA矫正改善了夜尿症以及其他LUTS。失败组未观察到这些改善。本研究表明OSA是夜尿症的一个病因,并且通过OSA的手术矫正可以改善其他LUTS和夜尿症。