Department of Otolaryngology, Asan Meidcal Center, University of Ulsan College of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2013 Sep;6(3):184-6. doi: 10.3342/ceo.2013.6.3.184. Epub 2013 Sep 4.
Burkitt's lymphoma is a highly aggressive small B-cell lymphoma. The treatment of choice is complex chemotherapy. As a rare tumor in the head and neck area, Burkitt's lymphoma usually involves cervical lymph nodes, and only fewer than 25% of cases involves extranodal regions. Involvement of the paranasal sinuses has been reported in only 14 cases in the past century. We describe here two patients with rare, sporadic, American type Burkitt's lymphoma involving the nasal cavity and paranasal sinuses manifesting nasal obstruction. We also review clinical and histological features of Burkitt's lymphoma.
伯基特淋巴瘤是一种高度侵袭性的小 B 细胞淋巴瘤。首选的治疗方法是复杂的化疗。作为头颈部罕见的肿瘤,伯基特淋巴瘤通常累及颈部淋巴结,只有不到 25%的病例累及结外区域。过去一个世纪,仅报道了 14 例累及副鼻窦的病例。我们在此描述了 2 例罕见的、散发的、美国型伯基特淋巴瘤患者,累及鼻腔和副鼻窦,表现为鼻塞。我们还回顾了伯基特淋巴瘤的临床和组织学特征。