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宫颈环扎术作为宫颈机能不全治疗选择的应用:肯尼亚一家中心9年期间的患者特征、临床表现及管理

Use of cervical cerclage as a treatment option for cervical incompetence: patient characteristics, presentation and management over a 9 year period in a Kenyan centre.

作者信息

Karau Paul B, Mutwiri Mwikamba G, Ogeng'o Julius A, Karau Geoffrey M

机构信息

Kenya Methodist University, School of Medicine, Department of Human Anatomy, Meru, Kenya.

出版信息

Afr J Reprod Health. 2013 Mar;17(1):169-73.

Abstract

Treatment of cervical incompetence by cerclage and other methods has yet to be standardized, as its diagnosis is not uniformly accepted. Its diagnosis, particularly in the African setting, is mostly based on past obstetric history of pregnancy losses, while in developed centres; ultrasound diagnosis is increasingly being used. The mainstay of treatment in developing countries is cervical cerclage, although the indications and contraindications of this mode of treatment are not documented. Our aim was to appraise this practice in terms of patient characteristics, the diagnostic process and management at the Kenyatta National Hospital, Nairobi, Kenya. This was a descriptive retrospective study over 9 years. Predesigned questionnaires were employed to collect data on patient's socio-demographic profile, presentation, risk factors, diagnosis and management of cervical incompetence. Chi-squared test and student's t-test were used to correlate variables. A total of 199 patients were treated for cervical incompetence, with the patient mean age being 27.97. 87.4% of the patients (p = 0.02) were in the 20 to 35 years category. Most of the patients (60.1%) were of low socio-economic status. Cervical cerclage was employed in all the patients, although ultrasound investigation was not employed in 65.8% of them. Diagnosis of cervical incompetence still relies on history of previous pregnancy losses, with the standard transvaginal ultrasound relatively unemployed. There is need to intensify investigations for this condition, standardize the indications for cerclage, and diversify management to other newer modalities.

摘要

由于宫颈机能不全的诊断尚未得到统一认可,通过宫颈环扎术和其他方法进行治疗也尚未标准化。其诊断,尤其是在非洲地区,主要基于既往妊娠丢失的产科病史,而在发达地区,超声诊断的应用越来越广泛。在发展中国家,治疗的主要方法是宫颈环扎术,尽管这种治疗方式的适应证和禁忌证尚无记录。我们的目的是根据肯尼亚内罗毕肯雅塔国家医院患者的特征、诊断过程和治疗情况来评估这种做法。这是一项为期9年的描述性回顾性研究。采用预先设计的问卷收集患者的社会人口统计学资料、临床表现、危险因素、宫颈机能不全的诊断和治疗情况。使用卡方检验和学生t检验来关联变量。共有199例患者接受了宫颈机能不全的治疗,患者平均年龄为27.97岁。87.4%的患者(p = 0.02)年龄在20至35岁之间。大多数患者(60.1%)社会经济地位较低。所有患者均采用了宫颈环扎术,尽管其中65.8%的患者未进行超声检查。宫颈机能不全的诊断仍然依赖于既往妊娠丢失的病史,标准的经阴道超声相对较少使用。有必要加强对这种疾病进行检查,规范宫颈环扎术的适应证,并使治疗方式多样化,采用其他更新的方法。

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