Fujimoto Motoaki, Shobayashi Yasuhiro, Takemoto Koichiro, Tateshima Satoshi, Viñuela Fernando
Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles; Los Angeles, CA, USA - E-mail:
Interv Neuroradiol. 2013 Sep;19(3):271-5. doi: 10.1177/159101991301900302. Epub 2013 Sep 26.
Perforator infarction represents a critical problem after intracranial Wingspan stent. To explore the mechanism of perforator infarction, we simulated the stent-artery interaction at an atheromatous plaque with perforator. Structural deformation and biomechanical stress distribution after stenting were analyzed. High radial stress values were located along the stent struts, which surrounded the area with high circumferential stress. Stretched perforator orifice in a circumferential direction after stenting was simulated. These results show that structural deformation could play a role in the mechanism of perforator occlusion after Wingspan stenting.
穿支动脉梗死是颅内Wingspan支架置入术后的一个关键问题。为了探究穿支动脉梗死的机制,我们模拟了在伴有穿支动脉的动脉粥样硬化斑块处的支架-动脉相互作用。分析了支架置入后的结构变形和生物力学应力分布。较高的径向应力值位于支架支柱周围,而这些支柱又环绕着高周向应力区域。模拟了支架置入后穿支动脉开口在周向方向上的拉伸情况。这些结果表明,结构变形可能在Wingspan支架置入术后穿支动脉闭塞的机制中发挥作用。