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用于症状性颅内动脉狭窄的Neuroform EZ支架置入术:在一个高容量卒中中心的30天结果

Neuroform EZ Stenting for Symptomatic Intracranial Artery Stenosis: 30 Days Outcomes in a High-Volume Stroke Center.

作者信息

Xu Haowen, Quan Tao, Zaidat Osama O, Chen Dapu, Wang Zibo, Yuan Yongjie, Yan Baojun, Lu Hong, Guan Sheng

机构信息

Departments of Interventional Neuroradiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Departments of Endovascular Neurosurgery and Stroke, St. Vincent Mercy Medical Center, Toledo, OH, United States.

出版信息

Front Neurol. 2019 May 16;10:428. doi: 10.3389/fneur.2019.00428. eCollection 2019.

Abstract

To test whether Neuroform EZ stent placement combined with the modified techniques in symptomatic severe intracranial stenosis (ICAS) would result in lower rates of peri-procedural complications of intracranial stenting. We retrospectively reviewed the clinical data from 71 consecutive patients who underwent Neuroform EZ stent placement combined with the modified techniques for symptomatic severe ICAS at our institute between January 2016 and October 2017. The primary outcomes were ipsi-lateral ischemic stroke, intra-cerebral hemorrhage, or death within 30 days after stenting. The secondary outcome was technical success. The technical success rate was 100%. The mean pre and post-stent stenoses were 84.2% ± 9.1% (median 85%, IQR75% to 90%) and 16.9% ± 10.2 % (median 15%, IQR 10% to 25%). The frequency of ipsi-lateral stroke, intra-cerebral hemorrhage, or death within 30 days was 0%. The combined use of Neuroform EZ stent placement and the modified techniques for symptomatic severe ICAS is technically feasible and safe, with very low peri-procedural complications. Further studies are required to assess the long-term results of this approach.

摘要

为了测试Neuroform EZ支架置入术联合改良技术用于症状性严重颅内动脉狭窄(ICAS)时是否会降低颅内支架置入术围手术期并发症的发生率。我们回顾性分析了2016年1月至2017年10月期间在我院连续71例行Neuroform EZ支架置入术联合改良技术治疗症状性严重ICAS患者的临床资料。主要结局为支架置入术后30天内同侧缺血性卒中、脑出血或死亡。次要结局为技术成功率。技术成功率为100%。支架置入术前、后的平均狭窄率分别为84.2%±9.1%(中位数85%,四分位间距75%至90%)和16.9%±10.2%(中位数15%,四分位间距10%至25%)。30天内同侧卒中、脑出血或死亡的发生率为0%。Neuroform EZ支架置入术联合改良技术用于症状性严重ICAS在技术上是可行且安全的,围手术期并发症发生率极低。需要进一步研究来评估这种方法的长期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c800/6532552/0ea3efa573bb/fneur-10-00428-g0001.jpg

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