Department of Infectious Diseases, Hvidovre University Hospital, Hvidovre, Denmark.
J Hosp Infect. 2013 Nov;85(3):237-9. doi: 10.1016/j.jhin.2013.08.005. Epub 2013 Sep 8.
Brucella species are a frequent cause of laboratory-acquired infections. This report describes the handling of a laboratory exposure of 17 laboratory staff members exposed to Brucella melitensis in a large microbiology laboratory in a brucella-non-endemic area. We followed the US Centers for Disease Control and Prevention guidelines, but, of 14 staff members classified as high-risk exposure, none accepted post-exposure prophylaxis. However, in a period of 6 months of follow-up, none of the exposed laboratory workers developed brucellosis and all obtained sera were negative for antibrucella antibodies. We therefore question the value of routine serological follow-up.
布鲁氏菌属是实验室获得性感染的常见原因。本报告描述了在布鲁氏菌非流行地区的一个大型微生物实验室中，17 名实验室工作人员接触到布鲁氏菌属时的实验室暴露处理情况。我们遵循了美国疾病控制与预防中心的指南，但在 14 名被归类为高风险暴露的工作人员中，没有人接受了接触后预防。然而，在 6 个月的随访期间，没有接触过实验室的工作人员患上布鲁氏菌病，所有接触过的血清均为抗布鲁氏菌抗体阴性。因此，我们质疑常规血清学随访的价值。
