Dubois F, Teby A, Belleville F, Nabet P, Paysant P
Département de Biochimie Clinique, CHU Brabois, Van-Doeuvre-Les-Nancy.
Ann Biol Clin (Paris). 1990;48(1):28-32.
Eastern France is a low selenium area. Livestock grazing on this soil had low selenium concentration. In human adults, the serum selenium levels were 0.91 +/- 0.14 mumol/l (n = 125) lower than in other european countries except Finland and Greece. However, no adult had serum concentration less than 0.57 mumol/l, a value under which the risk of death from ischemic heart disease or from cancer seem be increased. In infants, serum selenium contents were low, they increased progressively and reached adult levels at about 4 years in our study. In elderly subjects above 70 years old, serum selenium values were significantly (p less than 0.0001) below those of adults (0.83 +/- 0.17 mumol/l). The selenium values diminished when age increases in this population. 4.5 per cent of these subjects had a level under 0.57 mumol/l.
法国东部是一个低硒地区。在此土壤上放牧的牲畜体内硒浓度较低。在成年人中,血清硒水平为0.91±0.14微摩尔/升(n = 125),低于除芬兰和希腊之外的其他欧洲国家。然而,没有成年人的血清浓度低于0.57微摩尔/升,低于这一数值时,死于缺血性心脏病或癌症的风险似乎会增加。在婴儿中,血清硒含量较低,在我们的研究中,其含量逐渐增加,约在4岁时达到成人水平。在70岁以上的老年人中,血清硒值显著(p < 0.0001)低于成年人(0.83±0.17微摩尔/升)。在这一人群中,硒值随年龄增长而降低。4.5%的这些受试者的硒水平低于