*Department of Ophthalmology, University of Erlangen-Nuremberg, Erlangen, Germany; and †Department of Ophthalmology, University of Cologne, Cologne, Germany.
Cornea. 2013 Nov;32(11):1418-22. doi: 10.1097/ICO.0b013e3182a6ea4f.
To describe the use of an accidentally torn Descemet membrane (DM) to successfully complete Descemet membrane endothelial keratoplasty (DMEK) surgery.
Retrospective, observational case series of 3 eyes of 3 patients undergoing DMEK with a DM accidentally torn into 2 pieces during graft preparation. The mean outcome measures included best-corrected visual acuity, endothelial cell density, and central corneal thickness, before and at 1, 3, and 6 months after the DMEK surgery was performed.
During graft preparation, immediately before transplantation, a large tear within the 8.0-mm marking line of the DM occurred, resulting in a DM torn into 2 pieces. In all the eyes, both pieces were successfully implanted into the anterior chamber, unfolded and attached to the posterior corneal stroma, one after the other. Six months after the surgery was performed, the best-corrected visual acuity ranged between 20/30 and 20/25. Endothelial cell loss was about 30% (range 28%-32%) 6 months after the surgery. Pachymetry findings showed normal corneal thickness 6 months after the surgery. All corneas remained clear without any signs of graft failure within 6 months of follow-up.
DMEK surgery can be successfully completed despite the accidental tearing of donor DMs during the preparation of DMEK grafts by the sequential implantation of both DM pieces.
描述使用意外撕裂的后弹力膜(Descemet membrane,DM)成功完成后弹力膜内皮角膜移植术(Descemet membrane endothelial keratoplasty,DMEK)的情况。
回顾性观察性病例系列研究,纳入 3 名患者的 3 只眼,这些患者在准备供体 DMEK 移植物时,DM 意外撕裂成 2 块,随后行 DMEK 手术。主要结局指标包括术前和术后 1、3、6 个月的最佳矫正视力、内皮细胞密度和中央角膜厚度。
在准备移植物时,DM 的 8.0mm 标记线内发生了一个大的撕裂,导致 DM 撕裂成 2 块。在所有眼中,2 块 DM 均成功植入前房,先后展开并附着于后角膜基质。术后 6 个月,最佳矫正视力在 20/30 到 20/25 之间。术后 6 个月内皮细胞丢失约 30%(范围为 28%-32%)。角膜厚度测量结果显示术后 6 个月角膜正常。在 6 个月的随访期间,所有角膜均保持透明,没有任何移植物失败的迹象。
尽管在准备 DMEK 移植物时 DM 意外撕裂,但通过先后植入 2 块 DM 仍可成功完成 DMEK 手术。