Apomorphine-like effect of an aminotetralin on the linguomandibular reflex of the cat.
作者信息
Ilhan M, Nichols D E, Long J P, Cannon J G
出版信息
Eur J Pharmacol. 1975 Aug;33(1):61-4. doi: 10.1016/0014-2999(75)90138-7.
PMID:240731
Abstract
Low doses of 5,6-dihydroxy-2-dimethylaminotetralin (M-7) produced inhibition of the linguomandibular reflex in the cat. This inhibition was similar to that produced by apomorphine and was blocked by haloperidol, bulbocapnine or chlorpromazine. M-7 also had a brief but marked hypertensive effect. Gradual bradycardia also developed. These results indicate that M-7 inhibits the linguomandibular reflex by interaction at dopamine receptors, or 'apomorphine' receptors.
摘要
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