Complete remission of brain metastases of ovarian cancer following high-dose carboplatin: a case report and pharmacokinetic study.
作者信息
Vlasveld L T, Beynen J H, Boogerd W, Ten Bokkel Huinink W W, Rodenhuis S
机构信息
Clinical Research Unit, Netherlands Cancer Institute, Amsterdam.
出版信息
Cancer Chemother Pharmacol. 1990;25(5):382-3. doi: 10.1007/BF00686244.
PMID:2407368
Abstract
Brain metastases developed in a 40-year-old woman with relapsed ovarian cancer 2 years after cisplatin-based combination chemotherapy. After a single dose of 800 mg/m2 carboplatin, complete remission of the brain metastases occurred. A pharmacokinetic study during the second course revealed low levels of carboplatin in the cerebrospinal fluid.
摘要
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