a Department of Psychology , University of Hull , Hull , UK.
Cogn Neurosci. 2013;4(1):7-11. doi: 10.1080/17588928.2011.638139. Epub 2012 Jan 10.
In delay discounting tasks, participants decide between receiving a certain amount of money now or a larger sum sometime in the future. This study investigated the effects of transcranial direct current stimulation on delay discounting. Participants made delay discounting choices while receiving a bi-frontal stimulation of right-hemisphere anodal/left-hemisphere cathodal, left-hemisphere anodal/right-hemisphere cathodal, and sham stimulation, in three separate sessions. When the difference between the alternatives was 10% or more, participants generally preferred to wait for the larger sum. Nevertheless, there were more choices of smaller "immediate" gains, instead of the larger delayed options, when the left dorsolateral prefrontal cortex (DLPFC) was facilitated and the right DLPFC inhibited, compared to the sham stimulation. These observations indicate the significant role of the prefrontal cortex in delay discounting choices, and demonstrate that increased left frontal activation combined with decreased right frontal activation can alter decision-making by intensifying a tendency to choose immediate gains.
在延迟折扣任务中，参与者需要在现在获得一定数量的钱和未来某个时间获得更大数额的钱之间做出选择。本研究调查了经颅直流电刺激对延迟折扣的影响。参与者在接受右半球阳极/左半球阴极、左半球阳极/右半球阴极和假刺激的双额叶刺激的三个不同会话中做出延迟折扣选择。当选择之间的差异为 10%或更大时，参与者通常更愿意等待更大的金额。然而，与假刺激相比，当左背外侧前额叶皮层（DLPFC）被激活而右 DLPFC 被抑制时，参与者更倾向于选择较小的“即时”收益，而不是较大的延迟选项。这些观察结果表明前额叶皮层在延迟折扣选择中起着重要作用，并表明增加左额激活并结合减少右额激活可以通过加强选择即时收益的倾向来改变决策。
