a Outpatient Drug Clinic of Vall d'Hebron Hospital and Barcelona Public Health Agency (ASPB) , Barcelona , Spain.
J Addict Dis. 2013;32(3):263-73. doi: 10.1080/10550887.2013.824330.
Cocaine-dependent patients have high impulsiveness. Cocaine-induced psychosis is common among cocaine-dependent patients. Different risk factors associated with cocaine-induced psychosis have been reported. The aim of this study is to analyze the relationship between psychotic symptoms in cocaine-dependent patients and impulsivity and mental disorders characterized by impulsivity. This descriptive study included 287 outpatients with cocaine dependence according to the DSM-IV-TR criteria. The Structured Clinical Interview for DSM-IV Axis I and II, the Barratt Impulsiveness Scale, and a specific questionnaire on the presence of cocaine-induced psychosis were used to assess patients. Symptoms were observed in 59.9% of the study population. Total and cognitive impulsiveness scores obtained from the Barratt Impulsiveness Scale were significantly higher in patients with cocaine-induced psychosis. Individuals from this group reported more overdose incidents, initiated more treatments during their lifetime, and had a significantly greater prevalence of attention deficit hyperactivity disorder. Patients with cocaine-induced psychosis have a greater degree of impulsivity and a higher prevalence of attention deficit hyperactivity disorder. Thus, if these disorders are observed in cocaine-dependent participants, the presence of psychotic symptoms should be evaluated to prevent further occurrence and their consequences.
可卡因依赖患者具有较高的冲动性。可卡因引起的精神病在可卡因依赖患者中很常见。已经报道了与可卡因引起的精神病相关的不同风险因素。本研究旨在分析可卡因依赖患者的精神病症状与冲动性和以冲动性为特征的精神障碍之间的关系。这项描述性研究包括了根据 DSM-IV-TR 标准诊断为可卡因依赖的 287 名门诊患者。使用 DSM-IV 轴 I 和 II 结构临床访谈、巴瑞特冲动量表和专门的可卡因引起的精神病问卷评估患者。研究人群中 59.9%存在症状。从巴瑞特冲动量表中获得的总冲动和认知冲动评分在可卡因引起的精神病患者中明显更高。该组的个体报告了更多的过量用药事件，在他们的一生中开始了更多的治疗，并且注意力缺陷多动障碍的患病率明显更高。可卡因引起的精神病患者具有更高程度的冲动性和更高的注意力缺陷多动障碍患病率。因此，如果在可卡因依赖的参与者中观察到这些障碍，应评估是否存在精神病症状，以防止进一步发生及其后果。
